Agerschou, E.D. and Prchalova, T. and Simek, M. and Malý, M. and Stransky, J. and Strnad, M. and Santisteban-Veiga, A. and Williams, Mark and Sabín, J. and Dohnálek, J. (2025) Molecular Biophysics Database (MBDB) makes raw measurements findable and reusable. European Biophysics Journal , ISSN 0175-7571.
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Abstract
Open science is now established as an important paradigm for publicly funded research. The main principle being that to ensure best use of research data and integrity of the scientific process the information from experiments should be made widely and freely available. However, dedicated technical infrastructure to enable useful access to comprehensive experimental information in molecular biophysics is lacking, in particular in regard to repositories for raw measurement data. The Molecular Biophysics Database (MBDB) was created to fill this gap. The MBDB provides a common and extensible framework to store and access raw measurement data from a growing number of biophysical methods, currently including bio-layer interferometry, isothermal titration calorimetry, surface plasmon resonance, and microscale thermophoresis, with additional methods planned for the future. Alongside the raw measurement data from these methods, a rich set of metadata to enable data reuse is captured in accordance with the FAIR data management principles. An overview of the data models and technologies that were used to create the MBDB is presented here.
Metadata
| Item Type: | Article |
|---|---|
| Keyword(s) / Subject(s): | Molecular biophysics, Open Data, repository, raw data, FAIR principles |
| School: | Birkbeck Faculties and Schools > Faculty of Science > School of Natural Sciences |
| Research Centres and Institutes: | Structural Molecular Biology, Institute of (ISMB) |
| Depositing User: | Mark Williams |
| Date Deposited: | 05 Sep 2025 13:34 |
| Last Modified: | 11 Sep 2025 16:14 |
| URI: | https://eprints.bbk.ac.uk/id/eprint/56116 |
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