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Roddan, R. and Subrizi, F. and Broomfield, J. and Ward, J.M. and Keep, Nick and Hailes, H.C. (2021) Chemoenzymatic cascades toward Methylated Tetrahydroprotoberberine and Protoberberine Alkaloids. Organic Letters 23 (16), pp. 6342-6347. ISSN 1523-7060.
Maitra, A. and Evangelopoulos, D. and Chrzastek, A. and Martin, L.T. and Hanrath, A. and Chapman, E. and Hailes, H.C. and Lipman, M. and McHugh, T.D. and Waddell, S.J. and Bhakta, Sanjib (2020) Carprofen elicits pleiotropic mechanisms of bactericidal action with the potential to reverse antimicrobial drug resistance in tuberculosis. The Journal of Antimicrobial Chemotherapy 75 (11), pp. 3194-3201. ISSN 1460-2091.
Roddan, R. and Ward, J.M. and Keep, Nicholas H. and Hailes, H.C. (2020) Pictet-Spenglerases in Alkaloid Biosynthesis: future applications in Biocatalysis. Current Opinion in Chemical Biology 55 , pp. 69-76. ISSN 1367-5931.
Roddan, Rebecca and Gygli, G. and Sula, Altin and Méndez-Sánchez, D. and Pleiss, J. and Ward, J.M. and Keep, Nicholas H. and Hailes, H.C. (2019) The acceptance and kinetic resolution of alpha-Methyl Substituted Aldehydes by Norcoclaurine Synthase. ACS Catalysis 9 (10), pp. 9640-9649. ISSN 2155-5435.
Guzman, Juan D. and Pesnot, T. and Barrera, D.A. and Davies, H.M. and McMahon, E. and Evangelopoulos, Dimitrios and Mortazavi, Parisa Nakhostin and Munshi, Tulika and Maitra, Arundhati and Lamming, E.D. and Angell, R. and Gershater, M.C. and Redmond, J.M. and Needham, D. and Ward, J.M. and Cuca, L.E. and Hailes, H.C. and Bhakta, Sanjib (2015) Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase. Journal of Antimicrobial Chemotherapy 70 (6), pp. 1691-1703. ISSN 0305-7453.
Lichman, B.R. and Gershater, M.C. and Lamming, E.D. and Pesnot, T. and Sula, Altin and Keep, Nicholas H. and Hailes, H.C. and Ward, J.M. (2015) 'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile. FEBS Journal 282 (6), pp. 1137-1151. ISSN 1742-464X.