Browse by Person

Article

Szkop, Krzysztof J. and Moss, David S. and Nobeli, Irene (2021) flexiMAP: a regression-based method for discovering differential alternative polyadenylation events in standard RNA-seq data. Bioinformatics 37 (10), pp. 1461-1464. ISSN 1367-4803.

Stejskal, L. and Lees, William D. and Moss, David S. and Palor, M. and Bingham, R.J. and Shepherd, Adrian J. and Grove, J. (2020) Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein. PLoS Computational Biology 16 (2), e1007710. ISSN 1553-7358.

Hart, D.P. and Uzun, Nazmiye and Skelton, S. and Kakoschke, A. and Househam, J. and Moss, David S. and Shepherd, Adrian J. (2018) Factor VIII cross-matches to the human proteome reduce the predicted inhibitor risk in missense mutation hemophilia A. Haematologica 103 (10), ISSN 0390-6078.

Szkop, Krzysztof J. and Cooke, Peter I.C. and Humphries, Joanne A. and Kalna, Viktoria and Moss, David S. and Schuster, E.F. and Nobeli, Irene (2017) Dysregulation of alternative poly-adenylation as a potential player in Autism Spectrum Disorder. Frontiers in Molecular Neuroscience 10 , ISSN 1662-5099.

Shepherd, Adrian J. and Skelton, Stuart and Sansom, Clare E. and Gomez, K. and Moss, David S. and Hart, D.P. (2015) A large-scale computational study of inhibitor risk in non-severe haemophilia A. British Journal of Haematology 168 (3), pp. 413-420. ISSN 0007-1048.

Pentiah, Kevin and Lees, William D. and Moss, David S. and Shepherd, Adrian J. (2015) N-linked glycans on influenza A H3N2 hemagglutinin constrain binding of host antibodies, but shielding is limited. Glycobiology 25 (1), pp. 124-132. ISSN 0959-6658.

Yelland, T.S. and Naylor, Claire E. and Bagoban, T. and Savva, Christos G. and Moss, David S. and McClane, B.A. and Blasig, I.E. and Popoff, M. and Basak, Ajit K. (2014) Structure of a C. perfringens Enterotoxin mutant in complex with a Modified Claudin-2 Extracellular Loop 2. Journal of Molecular Biology 426 (18), pp. 3134-3147. ISSN 0022-2836.

Bokori-Brown, M. and Hall, C.A. and Vance, C. and Fernandes da Costa, S.P. and Savva, Christos G. and Naylor, Claire E. and Cole, Ambrose R. and Basak, Ajit K. and Moss, David S. and Titball, R.W. (2014) Clostridium perfringens epsilon toxin mutant Y30A-Y196A as a recombinant vaccine candidate against enterotoxemia. Vaccine 32 (23), pp. 2682-2687. ISSN 0264-410X.

da Costa, S. and Savva, Christos G. and Bokori-Brown, M. and Naylor, Claire E. and Moss, David S. and Basak, Ajit K. and Titball, R. (2014) Identification of a key residue for Oligomerisation and pore-formation of Clostridium perfringens NetB. Toxins 6 (3), pp. 1049-1061. ISSN 2072-6651.

Lees, William D. and Moss, David S. and Shepherd, Adrian J. (2014) Evolution in the influenza A H3 stalk - a challenge for broad-spectrum vaccines? Journal of General Virology 95 (2), pp. 317-324. ISSN 0022-1317.

Bokori-Brown, M. and Kokkinidou, M.C. and Savva, Christos G. and Fernandes da Costa, S.P. and Naylor, Claire E. and Cole, Ambrose R. and Moss, David S. and Basak, Ajit K. and Titball, R.W. (2013) Clostridium perfringensepsilon toxin H149A mutant as a platform for receptor binding studies. Protein Science 22 (5), pp. 650-659. ISSN 0961-8368.

Bokori-Brown, M. and Kokkinidou, M.C. and Savva, Christos G. and Fernandes da Costa, S.P. and Naylor, Claire E. and Cole, Ambrose R. and Moss, David S. and Basak, Ajit K. and Titball, R.W. (2013) Clostridium perfringensepsilon toxin H149A mutant as a platform for receptor binding studies. Protein Science 22 (5), pp. 650-659. ISSN 0961-8368.

Savva, Christos G. and Fernandes da Costa, S.P. and Bokori-Brown, M. and Naylor, Claire E. and Cole, Ambrose R. and Moss, David S. and Titball, R.W. and Basak, Ajit K. (2013) Molecular architecture and functional analysis of NetB, a pore-forming toxin from Clostridium perfringens. Journal of Biological Chemistry 288 , pp. 3512-3522. ISSN 0021-9258.

Ashford, Paul and Moss, David S. and Alex, A. and Yeap, S.K. and Povia, Alice and Nobeli, Irene and Williams, Mark A. (2012) Visualization of variable binding pockets on protein surfaces by probabilistic analysis of related structure sets. BMC Bioinformatics 13 , p. 39. ISSN 1471-2105.

Briggs, David C. and Naylor, Claire E. and Smedley, J.G. and Lukoyanova, Natalya and Robertson, S. and Moss, David S. and McClane, B.A. and Basak, Ajit K. (2011) Structure of the food-poisoning Clostridium perfringens enterotoxin reveals similarity to the aerolysin-like pore-forming toxins. Journal of Molecular Biology 413 (1), pp. 138-149. ISSN 0022-2836.

Lees, William D. and Moss, David S. and Shepherd, Adrian J. (2011) Analysis of antigenically important residues in human influenza A virus in terms of B-cell epitopes. Journal of Virology 85 (17), pp. 8548-8555. ISSN 0022-538X.

Halling-Brown, Mark D. and Pappalardo, F. and Rapin, N. and Zhang, P. and Alemani, D. and Emerson, A. and Castiglione, F. and Duroux, P. and Pennisi, M. and Miotto, O. and Churchill, D. and Rossi, E. and Moss, David S. and Sansom, Clare E. and Bernaschi, M. and Lefranc, M.P. and Brunak, S. and Lund, O. and Motta, S. and Lollini, P.L. and Murgo, A. and Palladini, A. and Basford, K.E. and Brusic, V. and Shepherd, Adrian J. (2010) ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale. Philosophical Transactions of the Royal Society A 368 (1920), pp. 1799-1815. ISSN 0080-4614.

Lees, William D. and Moss, David S. and Shepherd, Adrian J. (2010) A computational analysis of the antigenic properties of Haemagglutinin in Influenza A H3N2. Bioinformatics 26 (11), pp. 1403-1408. ISSN 1367-4803.

Halling-Brown, Mark D. and Shaban, R. and Frampton, D. and Sansom, Clare E. and Davies, M.N. and Flower, D.R. and Duffield, M. and Titball, R.W. and Brusic, V. and Moss, David S. (2009) Proteins accessible to immune surveillance show significant T-cell epitope depletion: implications for vaccine design. Molecular Immunology 46 (13), pp. 2699-2705. ISSN 0161-5890.

Halling-Brown, Mark D. and Moss, David S. and Sansom, Clare E. and Shepherd, Adrian J. (2009) A computational grid framework for immunological applications. Philosophical Transactions of the Royal Society A 367 (1898), pp. 2705-2716. ISSN 1364-503X.

Pappalardo, F. and Halling-Brown, Mark D. and Rapin, N. and Zhang, P. and Alemani, D. and Emerson, A. and Paci, P. and Duroux, P. and Pennisi, M. and Palladini, A. and Miotto, O. and Churchill, D. and Rossi, E. and Shepherd, Adrian J. and Moss, David S. and Castiglione, F. and Bernaschi, M. and Lefranc, M.P. and Brunak, S. and Motta, S. and Lollini, P.L. and Basford, K.E. and Brusic, V. (2009) ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization. Briefings in Bioinformatics 10 (3), pp. 330-340. ISSN 1467-5463.

Pappalardo, F. and Zhang, P. and Halling-Brown, Mark D. and Basford, K.E. and Scalia, A. and Shepherd, Adrian J. and Moss, David S. and Motta, S. and Brusic, V. (2008) Computational simulations of the immune system for personalized medicine: state of the art and challenges. Current Pharmacogenomics and Personalized Medicine 6 (4), pp. 260-271. ISSN 1875-6921.

Halling-Brown, Mark D. and Moss, David S. and Shepherd, Adrian J. (2008) Towards a lightweight generic computational grid framework for biological research. BMC Bioninformatics 9 , ISSN 1471-2105.

Halling-Brown, Mark D. and Sansom, Clare E. and Davies, M.N. and Titball, R.W. and Moss, David S. (2008) Are bacterial vaccine antigens T-cell epitope depleted? Trends in Immunology 29 (8), pp. 374-379. ISSN 1471-4906.

Davies, M.N. and Secker, A. and Halling-Brown, Mark D. and Moss, David S. and Freitas, A.A. and Timmis, J. and Clark, E. and Flower, D.R. (2008) GPCRTree: online hierarchical classification of GPCR function. BMC Research Notes 1 , p. 67. ISSN 1756-0500.

Davies, M.N. and Lamikanra, A. and Sansom, Clare E. and Flower, D.R. and Moss, David S. and Travers, P.J. (2008) Identification of the HLA-DM/HLA-DR interface. Molecular Immunology 45 (4), pp. 1063-1070. ISSN 0161-5890.

Todman, S.J. and Halling-Brown, Mark D. and Davies, M.N. and Flower, D.R. and Kayikci, M. and Moss, David S. (2008) Toward the atomistic simulation of T cell epitopes automated construction of MHC: peptide structures for free energy calculations. Journal of Molecular Graphics and Modelling 26 (6), pp. 957-961. ISSN 1093-3263.

Davies, M.N. and Toseland, C.P. and Moss, David S. and Flower, D.R. (2006) Benchmarking pKa prediction. BMC Biochemistry 7 (articl), ISSN 1471-2091.

Davies, M.N. and Hattotuwagama, C.K. and Moss, David S. and Drew, M.G.B. and Flower, D.R. (2006) Statistical deconvolution of enthalpic energetic contributions to MHC-peptide binding affinity. BMC Structural Biology 6 (articl), ISSN 1472-6807.