BIROn - Birkbeck Institutional Research Online
    Up a level
    Export as [feed] Atom [feed] RSS
    Number of items: 23.

    Article

    Szkop, Krzysztof J. and Moss, David S. and Nobeli, Irene (2021) flexiMAP: a regression-based method for discovering differential alternative polyadenylation events in standard RNA-seq data. Bioinformatics 37 (10), pp. 1461-1464. ISSN 1367-4803.

    Abelak, K. and Bishop-Bailey, D. and Nobeli, Irene (2019) Molecular dynamics simulations of the interaction of wild type and mutant human CYP2J2 with polyunsaturated fatty acids. BMC Research Notes , ISSN 1756-0500. (In Press)

    Ozuna, A. and Liberto, D. and Joyce, R.M. and Arnvig, K.B. and Nobeli, Irene (2019) baerhunter: an R package for the discovery and anal-ysis of expressed non-coding regions in bacterial RNA-seq data. Bioinformatics , ISSN 1460-2059. (In Press)

    Schwenk, S. and Moores, A. and Nobeli, Irene and McHugh, T.D. and Arnvig, K.B. (2018) Cell-wall synthesis and ribosome maturation are co-regulated by an RNA switch in Mycobacterium tuberculosis. Nucleic Acids Research , ISSN 0305-1048.

    Szkop, Krzysztof and Nobeli, Irene (2017) Untranslated parts of genes interpreted: making heads or tails of high-throughput transcriptomic data via computational methods. BioEssays 39 (12), ISSN 0265-9247.

    Szkop, Krzysztof J. and Cooke, Peter I.C. and Humphries, Joanne A. and Kalna, Viktoria and Moss, David S. and Schuster, E.F. and Nobeli, Irene (2017) Dysregulation of alternative poly-adenylation as a potential player in Autism Spectrum Disorder. Frontiers in Molecular Neuroscience 10 , ISSN 1662-5099.

    Smith, L.J. and Bochkareva, A. and Rolfe, M.D. and Hunt, D.M. and Kahramanoglou, C. and Braun, Y. and Rodgers, A. and Blockley, A. and Coade, S. and Lougheed, K.E.A. and Hafneh, N.A. and Glenn, S.M. and Crack, J.C. and Le Brun, N.E. and Saldanha, J.W. and Makarov, V. and Nobeli, Irene and Arnvig, K. and Mukamolova, G.V. and Buxton, R.S. and Green, J. (2017) Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence. Nucleic Acids Research 45 (11), pp. 6600-6612. ISSN 0305-1048.

    Lee, Hyunah and Patschull, Anathe and Bagneris, Claire and Ryan, H. and Sanderson, C.M. and Ebrahimi, B. and Nobeli, Irene and Barrett, Tracey E. (2017) KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing. Nucleic Acids Research 45 (8), pp. 4756-4767. ISSN 0305-1048.

    Proietti, G and Abelak, K.K. and Bishop-Bailey, D. and Macchiarulo, A. and Nobeli, Irene (2016) Computational modelling of the binding of arachidonic acid to the human monooxygenase CYP2J2. Journal of Molecular Modeling 22 (11), p. 279. ISSN 1610-2940.

    Bagneris, Claire and DeCaen, P.G. and Naylor, Claire E. and Pryde, D.C. and Nobeli, Irene and Clapham, D.E. and Wallace, Bonnie A. (2014) Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism. Proceedings of the National Academy of Sciences of the United States of America 111 (23), pp. 8428-8433. ISSN 0027-8424.

    Czarnecki, Jan M. and Nobeli, Irene and Smith, Adrian M.L. and Shepherd, Adrian J. (2012) A text-mining system for extracting metabolic reactions from full-text articles. BMC Bioinformatics 13 (172), ISSN 1471-2105.

    Patschull, Anathe O.M. and Gooptu, Bibek and Ashford, Paul and Daviter, Tina and Nobeli, Irene (2012) In silico assessment of potential druggable pockets on the surface of α1-Antitrypsin conformers. PLoS One 7 (5), ISSN 1932-6203.

    Ashford, Paul and Moss, David S. and Alex, A. and Yeap, S.K. and Povia, Alice and Nobeli, Irene and Williams, Mark A. (2012) Visualization of variable binding pockets on protein surfaces by probabilistic analysis of related structure sets. BMC Bioinformatics 13 , p. 39. ISSN 1471-2105.

    Guzman, Juan D. and Wube, A. and Evangelopoulos, Dimitrios and Gupta, Antima and Hufner, A. and Basavannacharya, Chandrakala and Rahman, M.M. and Thomaschitz, C. and Bauer, R. and McHugh, T.D. and Nobeli, Irene and Prieto, J.M. and Gibbons, S. and Bucar, F. and Bhakta, Sanjib (2011) Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics. Journal of Antimicrobial Chemotherapy 66 (8), pp. 1766-1772. ISSN 0305-7453.

    Patschull, Anathe O.M. and Segu, Lakshmi and Nyon, Mun Peak and Lomas, D.A. and Nobeli, Irene and Barrett, Tracey E. and Gooptu, Bibek (2011) Therapeutic target-site variability in α1-antitrypsin characterized at high resolution. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 (12), pp. 1492-1497. ISSN 1744-3091.

    Macchiarulo, A. and Thornton, Janet M. and Nobeli, Irene (2009) Mapping human metabolic pathways in the small molecule chemical space. Journal of Chemical Information and Modelling 49 (10), pp. 2272-2289. ISSN 1549-9596.

    Gooptu, Bibek and Miranda, E. and Nobeli, Irene and Mallya, M. and Purkiss, Andrew G. and Leigh Brown, S.C. and Summers, C. and Phillips, R.L. and Lomas, D.A. and Barrett, Tracey E. (2009) Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of α1-Antitrypsin: implications for disease and drug design. Journal of Molecular Biology 387 (4), pp. 857-868. ISSN 0022-2836.

    Nobeli, Irene and Favia, A.D. and Thornton, Janet M. (2009) Protein promiscuity and its implications for biotechnology. Nature Biotechnology 27 , pp. 157-167. ISSN 1087-0156.

    Favia, A.D. and Nobeli, Irene and Glaser, F. and Thornton, Janet M. (2008) Molecular docking for substrate identification: the short-chain dehydrogenases/reductases. Journal of Molecular Biology 375 (3), pp. 855-874. ISSN 0022-2836.

    Bashton, M. and Nobeli, Irene and Thornton, Janet M. (2008) Procognate: a cognate ligand domain mapping for enzymes. Nucleic Acids Research 36 , D618-D622. ISSN 0305-1048.

    Book Section

    Chang, Y.-P. and Mahadeva, R. and Patschull, A.O.M. and Nobeli, Irene and Ekeowa, U.I. and McKay, A.R. and Thalassinos, Konstantinos and Irving, J.A. and Haq, I. and Nyon, Mun Peak and Christodoulou, John and Ordóñez, A. and Miranda, E. and Gooptu, Bibek (2011) Targeting serpins in high-throughput and structure-based drug design. In: Whisstock, J.C. and Bird, P.I. (eds.) Serpin Structure and Evolution. Methods In Enzymology 501. New York, U.S.: Elsevier, pp. 139-175. ISBN 9780123859501.

    Favia, A.D. and Nobeli, Irene (2011) Using chemical structure to infer biological function. In: Guha, R. and Bender, A. (eds.) Computational Approaches in Cheminformatics and Bioinformatics. Hoboken, U.S.: Wiley, pp. 211-238. ISBN 9780470384411.

    Conference or Workshop Item

    Thornton, Janet M. and Favia, A.D. and Nobeli, Irene and Furnham, N. (2008) The evolution of specificity in large protein families. In: 33rd FEBS Congress & 11th IUBMB Conference: Biochemistry of Cell Regulation, June 28-July 3 2008, Athens, Greece.

    This list was generated on Fri Oct 22 06:12:42 2021 BST.