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    Sarkans, U. and Chiu, W. and Collinson, L. and Darrow, M.C. and Ellenberg, J. and Grunwald, D. and Hériché, J.-K. and Iudin, A. and Martins, G.G. and Meehan, T. and Narayan, K. and Patwardhan, A. and Russell, M.R.G. and Saibil, Helen R. and Strambio-De-Castillia, C. and Swedlow, J.R. and Tischer, C. and Uhlmann, V. and Verkade, P. and Barlow, M. and Bayraktar, O. and Birney, E. and Catavitello, C. and Cawthorne, C. and Wagner-Conrad, S. and Duke, E. and Paul-Gilloteaux, P. and Gustin, E. and Harkiolaki, M. and Kankaanpää, P. and Lemberger, T. and McEntyre, J. and Moore, J. and Nicholls, A.W. and Onami, S. and Parkinson, H. and Parsons, M. and Romanchikova, M. and Sofroniew, N. and Swoger, J. and Utz, N. and Voortman, L.M. and Wong, F. and Zhang, P. and Kleywegt, G.J. and Brazma, A. (2021) REMBI: Recommended Metadata for Biological Images—enabling reuse of microscopy data in biology. Nature Methods , ISSN 1548-7091.

    Saibil, Helen R. (2021) The PDB and protein homeostasis: from chaperones to degradation and disaggregase machines. Journal of Biological Chemistry 296 , p. 100744. ISSN 0021-9258.

    Zhou, Y. and Peskett, T.R. and Landles, C. and Warner, J.B. and Sathasivam, K. and Smith, E.J. and Chen, S. and Wetzel, R. and Lashuel, H.A. and Bates, G.P. and Saibil, Helen R. (2021) Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington’s disease. Acta Neuropathologica Communications 9 (1), ISSN 2051-5960.

    Deville, C. and Franke, K. and Mogk, A. and Bukau, B. and Saibil, Helen R. (2019) Two-step activation mechanism of the ClpB Disaggregase for sequential substrate threading by the Main ATPase Motor. Cell Reports 27 (12), 3433-3446.e4. ISSN 2211-1247.

    Fitzpatrick, A.W.P. and Saibil, Helen R. (2019) Cryo-EM of amyloid fibrils and cellular aggregates. Current Opinion in Structural Biology 58 , pp. 34-42. ISSN 0959-440X.

    Terry, C. and Harniman, R.L. and Sells, J. and Wenborn, A. and Joiner, S. and Saibil, Helen R. and Miles, M.J. and Collinge, J. and Wadsworth, J.D.F. (2019) Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro. Scientific Reports 9 (1), p. 376. ISSN 2045-2322.

    Natesh, Ramanathan and Clare, Daniel K. and Farr, G.W. and Horwich, A.L. and Saibil, Helen R. (2018) A two-domain folding intermediate of RuBisCO in complex with the GroEL chaperonin. International Journal of Biological Macromolecules 118 (A), pp. 671-675. ISSN 1879-0003.

    Peskett, T.R. and Rau, F. and O'Driscoll, Jonathan and Patani, R and Lowe, Alan R. and Saibil, Helen R. (2018) A liquid to solid phase transition underlying pathological huntingtin exon1 aggregation. Molecular Cell 7 (4), P588-601.E6. ISSN 1097-2765.

    Thomas, J.A. and Tan, M.S.Y. and Bisson, C. and Borg, A. and Umrekar, T.R. and Hackett, F. and Hale, V.L. and Vizcay-Barrena, G. and Fleck, R.A. and Snijders, A. and Saibil, Helen R. and Blackman, M.J. (2018) A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells. Nature Microbiology 3 , pp. 447-455. ISSN 2058-5276.

    Brennan, A.J. and Law, R.H.P. and Conroy, P.J. and Noori, T. and Lukoyanova, Natalya and Saibil, Helen R. and Yagita, H. and Ciccone, A. and Verschoor, S. and Whisstock, J.C. and Trapani, J.A. and Voskoboinik, I. (2018) Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death & Differentiation 25 , pp. 1517-1529. ISSN 1350-9047.

    Saibil, Helen R. (2017) Blob-ology and biology of cryo-EM: an interview with Helen Saibil. BMC Biology 15 (1), ISSN 1741-7007.

    Deville, Celia and Carroni, Marta and Franke, K.B. and Topf, Maya and Bukau, B. and Mogk, A. and Saibil, Helen R. (2017) Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase. Science Advances 3 (8), e1701726. ISSN 2375-2548.

    Patwardhan, A. and Brandt, R. and Butcher, S.J and Collinson, L. and Gault, D. and Grünewald, K. and Hecksel, C. and Huiskonen, J.T. and Iudin, A. and Jones, M.L. and Korir, P.K. and Koster, A.J. and Lagerstedt, I. and Lawson, C.L. and Mastronarde, D. and McCormick, M. and Parkinson, H. and Rosenthal, P.B. and Saalfeld, S. and Saibil, Helen R. and Sarntivijai, S. and Solanes Valero, I. and Subramaniam, S. and Swedlow, J.R. and Tudose, I. and Winn, M. and Kleywegt, G.J. (2017) Building bridges between cellular and molecular structural biology. eLife 6 , ISSN 2050-084X.

    Clare, D.K. and Siebert, C.A. and Hecksel, C. and Hagen, C. and Mordhorst, V. and Grange, M. and Ashton, A.W. and Walsh, M.A. and Grünewald, K. and Saibil, Helen R. and Stuart, D.I. and Zhang, P. (2017) Electron Bio-Imaging Centre (eBIC): the UK national research facility for biological electron microscopy. Acta Crystallographica Section D Biological Crystallography 73 (6), pp. 488-495. ISSN 0907-4449.

    Hale, V.L. and Watermeyer, Jean and Hackett, F. and Vizcay-Barrena, G. and van Ooij, C. and Thomas, J.A. and Spink, M.C. and Harkiolaki, M. and Duke, E. and Fleck, R.A. and Blackman, M.J. and Saibil, Helen R. (2017) Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse inPlasmodium falciparumegress. Proceedings of the National Academy of Sciences of the United States of America 114 (13), pp. 3439-3444. ISSN 0027-8424.

    Leung, C. and Hodel, A.W. and Brennan, A. and Lukoyanova, N. and Tran, S. and House, C.M. and Kondos, S.C. and Whisstock, J.C. and Dunstone, M.A. and Trapani, J.A. and Voskoboinik, I. and Saibil, Helen R. and Hoogenboom, B.W. (2017) Real-time visualization of perforin nanopore assembly. Nature Nanotechnology , ISSN 1748-3387.

    Hodel, A.W. and Leung Shin Cheung, Carl and Dudkina, Natalia and Saibil, Helen R. and Hoogenboom, B.W. (2016) Atomic force microscopy of membrane pore formation by cholesterol dependent cytolysins. Current Opinion in Structural Biology 39 (1), pp. 8-15. ISSN 0959-440X.

    Lukoyanova, N. and Hoogenboom, B.W. and Saibil, Helen R. (2016) The membrane attack complex, perforin and cholesterol-dependent cytolysin superfamily of pore-forming proteins. Journal of Cell Science 129 (11), pp. 2125-2133. ISSN 0021-9533.

    Terry, C. and Wenborn, A. and Gros, N. and Sells, J. and Joiner, S. and Hosszu, L.L.P. and Tattum, M.H. and Panico, Silvia and Clare, Daniel and Collinge, J. and Saibil, Helen R. and Wadsworth, J.D.F. (2016) Ex vivomammalian prions are formed of paired double helical prion protein fibrils. Open Biology 6 (5), p. 160035. ISSN 2046-2441.

    Carroni, Marta and Saibil, Helen R. (2016) Cryo electron microscopy to determine the structure of macromolecular complexes. Methods 95 , pp. 78-85. ISSN 1046-2023.

    Dudkina, Natalya and Spicer, B.A. and Reboul, C.F. and Conroy, P.J. and Lukoyanova, Natalya and Elmlund, H. and Law, R.H.P. and Ekkel, S.M. and Kondos, S.C. and Goode, R.J.A. and Ramm, G. and Whisstock, J.C. and Saibil, Helen R. and Dunstone, M.A. (2016) Structure of the poly-C9 component of the complement membrane attack complex. Nature Communications 7 , p. 10588. ISSN 2041-1723.

    Watermeyer, Jean M. and Hale, Victoria L. and Hackett, F. and Clare, Daniel K. and Cutts, E.E. and Vakonakis, I. and Fleck, R.A. and Blackman, M.J. and Saibil, Helen R. (2016) A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes. Blood 127 (3), pp. 343-351. ISSN 0006-4971.

    Nans, Andrea and Kudryashev, M. and Saibil, Helen R. and Hayward, Richard D. (2015) Structure of a bacterial type III secretion system in contact with a host membrane in situ. Nature Communications 6 , p. 1104. ISSN 2041-1723.

    Das, S. and Hertrich, N. and Perrin, A.J. and Withers-Martinez, C. and Collins, C.R. and Jones, M.L. and Watermeyer, Jean M. and Fobes, E.T. and Martin, S.R. and Saibil, Helen R. and Wright, G.J. and Treeck, M. and Epp, C. and Blackman, M.J. (2015) Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 activates a Spectrin-binding function enabling parasite egress from RBCs. Cell Host & Microbe 18 (4), pp. 433-444. ISSN 1931-3128.

    O'Driscoll, Jonathan and Clare, Daniel K. and Saibil, Helen R. (2015) Prion aggregate structure in yeast cells is determined by the Hsp104-Hsp110 disaggregase machinery. The Journal of Cell Biology 211 (1), pp. 145-158. ISSN 0021-9525.

    Gao, X. and Carroni, Marta and Nussbaum-Krammer, C. and Mogk, A. and Nillegoda, N.B. and Szlachcic, A. and Guilbride, D.L. and Saibil, Helen R. and Mayer, M.P. and Bukau, B. (2015) Human Hsp70 Disaggregase reverses Parkinson’s-linked α-Synuclein Amyloid Fibrils. Molecular Cell 59 (5), pp. 781-793. ISSN 1097-2765.

    Sali, A. and Berman, H.M. and Schwede, T. and Trewhella, J. and Kleywegt, G. and Burley, S.K. and Markley, J. and Nakamura, H. and Adams, P. and Bonvin, A.M.J.J. and Wah, C. and Dal Peraro, M. and Di Maio, F. and Ferrin, T.E. and Grünewald, K. and Gutmanas, A. and Henderson, R. and Hummer, G. and Iawsaki, K. and Johnson, G. and Lawson, C.L. and Meiler, J. and Marti-Renom, M.A. and Montelione, G.T. and Nilges, M. and Nussinov, R. and Patwardhan, A. and Rappsilber, J. and Read, R.J. and Saibil, Helen R. and Schröder, G.F. and Schwieters, C. and Seidel, C.A.M. and Svergun, D. and Topf, Maya and Ulrich, E.L. and Velankar, S. and Westbrook, J.D. (2015) Outcome of the First wwPDB Hybrid / Integrative Methods Task Force Workshop. Structure 23 (7), pp. 1156-1167. ISSN 0969-2126.

    Wenborn, A. and Terry, C. and Gros, N. and Joiner, S. and D’Castro, L. and Panico, Silvia and Sells, J. and Cronier, S. and Linehan, J.M. and Brandner, S. and Saibil, Helen R. and Collinge, J. and Wadsworth, J.D.F. (2015) A novel and rapid method for obtaining high titre intact prion strains from mammalian brain. Scientific Reports 5 , p. 10062. ISSN 2045-2322.

    Lukoyanova, Natalya and Kondos, S.C. and Farabella, Irene and Law, R.H.P. and Reboul, C.F. and Caradoc-Davies, T.T. and Spicer, B.A. and Kleifeld, O. and Traore, D.A.K. and Ekkel, S.M. and Voskoboinik, I. and Trapani, J.A. and Hatfaludi, T. and Oliver, K. and Hotze, E.M. and Tweten, R.K. and Whisstock, J.C. and Topf, Maya and Saibil, Helen R. and Dunstone, M.A. (2015) Conformational changes during pore formation by the perforin-related protein pleurotolysin. PLoS Biology 13 (2), e1002049. ISSN 1545-7885.

    Dumoux, Maud and Nans, Andrea and Saibil, Helen R. and Hayward, Richard D. (2015) Making connections: snapshots of chlamydial type III secretion systems in contact with host membranes. Current Opinion in Microbiology 23 , pp. 1-7. ISSN 1369-5274.

    Saibil, Helen R. and Grünewald, K. and Stuart, D.I. (2015) A national facility for biological cryo-electron microscopy. Acta Crystallographica Section D Biological Crystallography 71 (1), pp. 127-135. ISSN 0907-4449.

    Leung, C. and Dudkina, N.V. and Lukoyanova, Natalya and Hodel, A.W. and Farabella, I. and Pandurangan, A.P. and Jahan, N. and Pires Damaso, M. and Osmanović, D. and Reboul, C.F. and Dunstone, M.A. and Andrew, P.W. and Lonnen, R. and Topf, Maya and Saibil, Helen R. and Hoogenboom, B.W. (2014) Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin. eLife 3 , ISSN 2050-084X.

    Patwardhan, A. and Ashton, A. and Brandt, R. and Butcher, S. and Carzaniga, R. and Chiu, W. and Collinson, L. and Doux, P. and Duke, E. and Ellisman, M.H. and Franken, E. and Grünewald, K. and Heriche, J.-K. and Koster, A. and Kühlbrandt, W. and Lagerstedt, I. and Larabell, C. and Lawson, C.L. and Saibil, Helen R. and Sanz-García, E. and Subramaniam, S. and Verkade, P. and Swedlow, J.R. and Kleywegt, G.J. (2014) A 3D cellular context for the macromolecular world. Nature Structural & Molecular Biology 21 (10), pp. 841-845. ISSN 1545-9993.

    Nans, Andrea and Saibil, Helen R. and Hayward, Richard (2014) Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography. Cellular Microbiology 16 (10), pp. 1457-1472. ISSN 1462-5814.

    Trevitt, C.R. and Hosszu, L.L.P. and Batchelor, M. and Panico, S. and Terry, C. and Nicoll, A.J. and Risse, E. and Taylor, W.A. and Sandberg, M.K. and Al-Doujaily, H. and Linehan, J.M. and Saibil, Helen R. and Scott, D.J. and Collinge, J. and Waltho, J.P. and Clarke, A.R. (2014) N-terminal domain of Prion Protein directs its Oligomeric Association. Journal of Biological Chemistry 289 , pp. 25497-25508. ISSN 0021-9258.

    Carroni, Marta and Kummer, E. and Oguchi, Y. and Wendler, P. and Clare, Daniel K. and Sinning, I. and Kopp, J. and Mogk, A. and Bukau, B. and Saibil, Helen R. (2014) Head-to-tail interactions of the coiled-coil domains regulate ClpB activity and cooperation with Hsp70 in protein disaggregation. eLife 3 , e02481-e02481. ISSN 2050-084X.

    Carroni, M. and Kummer, E. and Oguchi, Y. and Wendler, P. and Clare, D.K. and Sinning, I. and Kopp, J. and Mogk, A. and Bukau, B. and Saibil, Helen R. (2014) Head-to-tail interactions of the coiled-coil domains regulate ClpB cooperation with Hsp70 in protein disaggregation. eLife , ISSN 2050-084X.

    Clare, Daniel K. and Saibil, Helen R. (2013) ATP-driven molecular chaperone machines. Biopolymers 99 (11), pp. 846-859. ISSN 0006-3525.

    Saibil, Helen R. (2013) Chaperone machines for protein folding, unfolding and disaggregation. Nature Reviews Molecular Cell Biology 14 (10), pp. 630-642. ISSN 1471-0072.

    Housden, N.G. and Hopper, J.T.S. and Lukoyanova, Natalya and Rodriguez-Larrea, D. and Wojdyla, J.A. and Klein, A. and Kaminska, R. and Bayley, H. and Saibil, Helen R. and Robinson, C.V. and Kleanthous, C. (2013) Intrinsically disordered protein threads through the bacterial outer-membrane Porin OmpF. Science 340 (6140), pp. 1570-1574. ISSN 0036-8075.

    Saibil, Helen R. and Fenton, W. and Clare, Daniel K. and Horwich, A.L. (2013) Structure and allostery of the Chaperonin GroEL. Journal of Molecular Biology 425 (9), pp. 1476-1487. ISSN 0022-2836.

    Lopez, J.A. and Susanto, O. and Jenkins, M.R. and Lukoyanova, Natalya and Sutton, V.R. and Law, R.H.P. and Johnston, A. and Bird, C.H. and Bird, P I. and Whisstock, J.C. and Trapani, J.A. and Saibil, Helen R. and Voskoboinik, I. (2013) Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack. Blood 121 (14), pp. 2659-2668. ISSN 0006-4971.

    Saibil, Helen R. (2013) Machinery to reverse irreversible aggregates. Science 339 (6123), pp. 1040-1041. ISSN 0036-8075.

    Milanesi, Lilia and Sheynis, T. and Xue, W.-F. and Orlova, Elena and Hellewell, A.L. and Jelinek, R. and Hewitt, E.W. and Radford, S.E. and Saibil, Helen R. (2012) Direct three-dimensional visualization of membrane disruption by amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America 109 (50), pp. 20455-20460. ISSN 0027-8424.

    Dumoux, Maud and Clare, Daniel K. and Saibil, Helen R. and Hayward, Richard D. (2012) Chlamydiae assemble a pathogen synapse to hijack the host endoplasmic reticulum. Traffic 13 (12), pp. 1612-1617. ISSN 1398-9219.

    Lander, G.C. and Saibil, Helen R. and Nogales, E. (2012) Go hybrid: EM, crystallography, and beyond. Current Opinion in Structural Biology 22 (5), pp. 627-635. ISSN 0959-440X.

    Saibil, Helen R. and Seybert, A. and Habermann, A. and Winkler, J. and Eltsov, M. and Perkovic, M. and Castano-Diez, D. and Scheffer, M.P. and Haselmann, U. and Chlanda, P. and Lindquist, S. and Tyedmers, J. and Frangakis, A.S. (2012) Heritable yeast prions have a highly organized three-dimensional architecture with interfiber structures. Proceedings of the National Academy of Sciences of the United States of America 109 (37), pp. 14906-14911. ISSN 0027-8424.

    Clare, Daniel K. and Vasishtan, Daven and Stagg, S. and Quispe, J. and Farr, G.W. and Topf, Maya and Horwich, A.L. and Saibil, Helen R. (2012) ATP-triggered conformational changes delineate substrate-binding and -folding mechanics of the GroEL Chaperonin. Cell 149 (1), pp. 113-123. ISSN 0092-8674.

    Malet, Hélène and Canellas, F. and Sawa, J. and Yang, J. and Thalassinos, Konstantinos and Ehrmann, M. and Clausen, T. and Saibil, Helen R. (2012) Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ. Nature Structural & Molecular Biology 19 , pp. 152-157. ISSN 1545-9993.

    Freir, D.B. and Nicoll, A.J. and Klyubin, I. and Panico, Silvia and McDonald, J.M. and Risse, E. and Asante, E.A. and Farrow, M.A. and Sessions, R.B. and Saibil, Helen R. and Clarke, A.R. and Rowan, M.J. and Walsh, D.M. and Collinge, J. (2011) Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites. Nature Communications 2 , ISSN 2041-1723.

    Orlova, Elena and Saibil, Helen R. (2011) Structural analysis of macromolecular assemblies by electron microscopy. Chemical Reviews 111 (12), pp. 7710-7748. ISSN 0009-2665.

    Law, R.H.P. and Lukoyanova, Natalya and Voskoboinik, I. and Caradoc-Davies, T.T. and Baran, K. and Dunstone, M.A. and d’Angelo, M.E. and Orlova, Elena and Coulibaly, F. and Verschoor, S. and Browne, K.A. and Ciccone, A. and Kuiper, M.J. and Bird, P.I. and Trapani, J.A. and Saibil, Helen R. and Whisstock, J.C. (2010) The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature 468 (7322), pp. 447-451. ISSN 0028-0836.

    Benesch, J.L.P. and Ruotolo, B.T. and Simmons, D.A. and Barrera, N.P. and Morgner, N. and Wang, Luchun and Saibil, Helen R. and Robinson, C.V. (2010) Separating and visualising protein assemblies by means of preparative mass spectrometry and microscopy. Journal of Structural Biology 172 (2), pp. 161-168. ISSN 1047-8477.

    O'Donoghue, S.I. and Goodsell, D.S. and Frangakis, A.S. and Jossinet, F. and Laskowski, R.A. and Nilges, M. and Saibil, Helen R. and Schafferhans, A. and Wade, R.C. and Westhof, E. and Olson, A.J. (2010) Visualization of macromolecular structures. Nature Methods 7 (3(S)), S42-S55. ISSN 1548-7091.

    Wendler, Petra and Saibil, Helen R. (2010) Cryo electron microscopy structures of Hsp100 proteins: crowbars in or out? Biochemistry and Cell Biology 88 (1), pp. 89-96. ISSN 0829-8211.

    Malet, Hélène and Topf, Maya and Clare, Daniel K. and Ebert, J. and Bonneau, F. and Basquin, J. and Drazkowska, K. and Tomecki, R. and Dziembowski, A. and Conti, E. and Saibil, Helen R. and Lorentzen, Esben (2010) RNA channelling by the eukaryotic exosome. EMBO Reports 11 (12), pp. 936-942. ISSN 1469-221X.

    Tarry, M.J. and Schafer, Eva and Chen, S.Y. and Buchanan, G. and Greene, N.P. and Lea, S.M. and Palmer, T. and Saibil, Helen R. and Berks, B.C. (2009) Structural analysis of substrate binding by the TatBC component of the twin-arginine protein transport system. Proceedings of the National Academy of Sciences of the United States of America 106 (32), pp. 13284-13289. ISSN 0027-8424.

    White, Helen E. and Hodgkinson, J.L. and Jahn, T.R. and Cohen-Krausz, Sara and Gosal, W.S. and Muller, S. and Orlova, Elena and Radford, S.E. and Saibil, Helen R. (2009) Globular Tetramers of beta(2)-Microglobulin assemble into elaborate amyloid fibrils. Journal of Molecular Biology 389 (1), pp. 48-57. ISSN 0022-2836.

    Baran, K. and Dunstone, M.A. and Chia, J. and Ciccone, A. and Browne, K.A. and Clarke, C.J.P. and Lukoyanova, Natalya and Saibil, Helen R. and Whisstock, J.C. and Voskoboinik, I. and Trapani, J.A. (2009) The molecular basis for perforin oligomerization and transmembrane pore assembly. Immunity 30 (5), pp. 684-695. ISSN 1074-7613.

    Rey, F.A. and Saibil, Helen R. (2009) Macromolecular assemblies. Current Opinion in Structural Biology 19 (2), pp. 178-180. ISSN 0959-440X.

    Wendler, Petra and Shorter, J. and Snead, D. and Plisson, Celia and Clare, Daniel K. and Lindquist, S. and Saibil, Helen R. (2009) Motor mechanism for protein threading through Hsp104. Molecular Cell 34 (1), pp. 81-92. ISSN 1097-2765.

    Clare, Daniel K. and Bakkes, P.J. and van Heerikhuizen, H. and van der Vies, S.M. and Saibil, Helen R. (2009) Chaperonin complex with a newly folded protein encapsulated in the folding chamber. Nature (457), pp. 107-110. ISSN 0028-0836.

    Fronzes, Remi and Schafer, Eva and Wang, Luchun and Saibil, Helen R. and Orlova, Elena and Waksman, Gabriel (2009) Structure of a type IV secretion system core complex. Science 323 (5911), pp. 266-268. ISSN 0036-8075.

    Krojer, T. and Sawa, J. and Schafer, Eva and Saibil, Helen R. and Ehrmann, M. and Clausen, T. (2008) Structural basis for the regulated protease and chaperone function of DegP. Nature (453), pp. 885-890. ISSN 0028-0836.

    Elad, Nadav and Clare, Daniel K. and Saibil, Helen R. and Orlova, Elena (2008) Detection and separation of heterogeneity in molecular complexes by statistical analysis of their two-dimensional projections. Journal of Structural Biology 162 (1), pp. 108-120. ISSN 1047-8477.

    Clare, Daniel K. and Stagg, S. and Quispe, J. and Farr, G.W. and Horwich, A.L. and Saibil, Helen R. (2008) Multiple states of a Nucleotide-Bound Group 2 Chaperonin. Structure 16 (4), pp. 528-534. ISSN 0969-2126.

    Saibil, Helen R. (2008) Chaperone machines in action. Current Opinion in Structural Biology 18 (1), pp. 35-42. ISSN 0959-440X.

    Lukoyanova, Natalya and Saibil, Helen R. (2008) Friend or foe: the same fold for attack and defense. Trends in Immunology 29 (2), pp. 51-53. ISSN 1471-4906.

    Puri, T. and Wendler, Petra and Sigala, B. and Saibil, Helen R. and Tsaneva, I.R. (2007) Dodecameric structure and ATPase activity of the human TIP48/TIP49 complex. Journal of Molecular Biology 366 (1), 179 - 192. ISSN 0022-2836.

    Wendler, Petra and Shorter, J. and Plisson, Celia and Cashikar, A.G. and Lindquist, S. and Saibil, Helen R. (2007) Atypical AAA+ subunit packing creates an expanded cavity for disaggregation by the protein-remodeling factor Hsp104. Cell 131 (7), 1366 - 1377. ISSN 0092-8674.

    Elad, Nadav and Farr, G.W. and Clare, Daniel K. and Orlova, Elena and Horwich, A.L. and Saibil, Helen R. (2007) Topologies of a Substrate Protein Bound to the Chaperonin GroEL. Molecular Cell 26 (3), 415 - 426. ISSN 1097-2765.

    Tattum, M.H. and Cohen-Krausz, Sara and Khalili Shirazi, A. and Jackson, G.S. and Orlova, Elena and Collinge, J. and Clarke, A.R. and Saibil, Helen R. (2006) Elongated oligomers assemble into mammalian PrP Amyloid fibrils. Journal of Molecular Biology 357 (3), pp. 975-985. ISSN 0022-2836.

    Book Section

    Horwich, A.L. and Buchner, J. and Smock, R.G. and Gierasch, L.M. and Saibil, Helen R. (2012) Chaperones and protein folding. In: UNSPECIFIED (ed.) Comprehensive Biophysics. New York, U.S.: Elsevier, pp. 212-237. ISBN 9780080957180.

    Orlova, Elena and Saibil, Helen R. (2010) Methods for three-dimensional reconstruction of heterogeneous assemblies. In: Jensen, G.J. (ed.) Methods in Enzymology. Cryo-EM, Part B: 3-D Reconstruction. Philadelphia, USA: Elsevier, pp. 321-341. ISBN 9780123849915.

    This list was generated on Sat Dec 14 05:30:47 2024 GMT.