Browse by Research Centre

B

Bellot, Sidonie and Bayton, R.P. and Couvreur, T.L.P. and Dodsworth, Steven and Eiserhardt, W.L. and Guignard, M.S. and Pritchard, H.W. and Roberts, L. and Toorop, P.E. and Baker, W.J. (2020) On the origin of giant seeds: the macroevolution of the double coconut (Lodoicea maldivica) and its relatives (Borasseae, Arecaceae). New Phytologist 228 (3), pp. 1134-1148. ISSN 0028-646X.

C

Collins, A.M. and Yaari, G. and Shepherd, Adrian J. and Lees, William and Watson, C.T. (2020) Germline immunoglobulin genes: disease susceptibility genes hidden in plain sight? Current Opinion in Systems Biology 24 , pp. 100-108. ISSN 24523100.

D

Dodsworth, Steven and Guignard, M.S. and Pérez-Escobar, O.A. and Struebig, M. and Chase, M.W. and Leitch, A.R. (2020) Repetitive DNA restructuring across multiple Nicotiana allopolyploidisation events shows a lack of strong cytoplasmic bias in influencing repeat turnover. Genes 11 (2), ISSN 2073-4425.

Dodsworth, Steven and Kovarik, A. and Grandbastien, M.A. and Leitch, I.J. and Leitch, A.R. (2020) Repetitive DNA dynamics and polyploidization in the genus Nicotiana (Solanaceae). In: Ivanov, N.V. and Sierro, N. and Peitsch, M.C. (eds.) The Tobacco Genome. Compendium of Plant Genomes. Springer, pp. 85-99. ISBN 9783030294922.

G

Gradeci, D. and Bove, A. and Charras, G. and Lowe, Alan and Banerjee, S. (2020) Single-cell approaches to cell competition: high-throughput imaging, machine learning and simulations. Seminars in Cancer Biology 63 , pp. 60-68. ISSN 1044-579X.

Grey, W. and Chauhan, R. and Piganeau, M. and Huerga, E. and Garcia-Albornoz, M. and McDonald, Neil and Bonnet, D. (2020) Activation of the Receptor Tyrosine Kinase, RET, improves long-term Hematopoietic Stem Cell outgrowth and potency. Blood 136 (22), pp. 2535-2547. ISSN 0006-4971.

H

Hartley, Andrew and Meunier, B. and Pinotsis, Nikos and Marechal, Amandine (2020) Rcf2 revealed in cryoEM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes. Proceedings of the National Academy of Sciences of the United States of America 117 (17), pp. 9329-9337. ISSN 0027-8424.

J

Jones, M. and Beuron, F. and Borg, A. and Nans, A. and Earl, C.P. and Briggs, D.C. and Snijders, A.P. and Bowles, M. and Morris, E.P. and Linch, M. and McDonald, Neil Q. (2020) Cryo-EM structures of the XPF-ERCC1 endonuclease reveal how DNA-junction engagement disrupts an auto-inhibited conformation. Nature Communications 11 , p. 1120. ISSN 2041-1723.

K

Kramm, K. and Schroder, T. and Gouge, Jerome and Vera, A.M. and Gupta, K. and Heiss, F.B. and Engel, C. and Berger, I. and Vannini, A. and Tinnefeld, P. and Grohmann, D. (2020) DNA origami-based single-molecule forcespectroscopy elucidates RNA Polymerase IIIpre-initiation complex stability. Nature Communications 11 (2828), ISSN 2041-1723.

M

Marechal, Amandine and Xu, J.-Y. and Genko, N. and Hartley, Andrew and Haraux, F. and Meunier, B. and Rich, P. (2020) A common coupling mechanism for A-type heme-copper oxidases from bacteria to mitochondria. Proceedings of the National Academy of Sciences of the United States of America 117 (17), pp. 9349-9355. ISSN 0027-8424.

Moccia, M. and Frett, B. and Zhang, L. and Lakkaniga, R. and Briggs, D.C. and Chauhan, R. and Brescia, A. and Federico, G. and Santoro, M. and McDonald, Neil Q. and Li, H. and Carlomagno, F. (2020) Bioisosteric discovery of NPA101.3, a second generation RET/VEGFR2 inhibitor optimized for single-agent polypharmacology. Journal of Medicinal Chemistry 63 (9), pp. 4506-4516. ISSN 0022-2623.

O

Ozuna, A. and Liberto, D. and Joyce, R.M. and Arnvig, K.B. and Nobeli, Irene (2020) baerhunter: an R package for the discovery and anal-ysis of expressed non-coding regions in bacterial RNA-seq data. Bioinformatics 36 (3), pp. 966-969. ISSN 1460-2059.

P

Palor, M. and Stejskal, L. and Mandal, P. and Lenman, A. and Alberione, M.P. and Kirui, J. and Moeller, R. and Ebner, S. and Meissner, F. and Gerold, G. and Shepherd, Adrian and Grove, J. (2020) Cholesterol sensing by CD81 is important for hepatitis C virus entry. Journal of Biological Chemistry 295 (50), pp. 16931-16948. ISSN 0021-9258.

R

Ramsay, E.P. and Abascal-Palacios, G. and Daiß, J.L. and King, H. and Gouge, Jerome and Pilsl, M. and Beuron, F. and Morris, E. and Gunkel, P. and Engel, C. and Vannini, A. (2020) Structure of human RNA polymerase III. Nature Communications 11 (6409), ISSN 2041-1723.

Roddan, Rebecca and Keep, Nicholas H. and Sula, Altin (2020) Single step syntheses of (1 S)-aryltetrahydroisoquinolines by norcoclaurine synthases. Nature Communications 3 (170), ISSN 2041-1723.

S

Sachdeva, A. and Gouge, Jerome and Kontovounisios, C. and Nikolaou, S. and Ashworth, A. and Lim, K. and Chong, I. (2020) Klotho and the treatment of human malignancies. Cancers 12 (1665), ISSN 2072-6694.

Stancheva, V.G. and Li, X.-H. and Hutchings, Joshua and Gomez-Navarro, N. and Santhanam, B. and Babu, M. and Zanetti, Giulia and Miller, E.A. (2020) Combinatorial multivalent interactions drive cooperative assembly of the COPII coat. Journal of Cell Biology 219 (11), e202007135. ISSN 0021-9525.

V

Vakati, V. and Dodsworth, Steven (2020) Non-destructive genome skimming for aquatic copepods. Conservation Genetics Resources 12 (3), pp. 515-520. ISSN 1877-7260.

Vig, A. and Poulter, J.A. and Ottaviani, D. and Tavares, E. and Toropova, K. and Tracewska, A.M. and Mollica, A. and Kang, J. and Kehelwathugoda, O. and Paton, T. and Maynes, J.T. and Wheway, G. and Arno, G. and Genomics England Research, C. and Khan, K.N. and McKibbin, M. and Toomes, C. and Ali, M. and Di Scipio, M. and Li, S. and Ellingford, J. and Black, G. and Webster, A. and Rydzanicz, M. and Stawiński, P. and Płoski, R. and Vincent, A. and Cheetham, M.E. and Inglehearn, C.F. and Roberts, Anthony J. and Heon, E. (2020) DYNC2H1 hypomorphic or retina-predominant variants cause nonsyndromic retinal degeneration. Genetics in Medicine 22 (12), pp. 2041-2051. ISSN 1530-0366.