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Muselmani, Wael and Kashif-Khan, Naail and Bagneris, Claire and Santangelo, Rosalia and Williams, Mark A and Savva, Renos (2023) A multimodal approach towards genomic identification of protein inhibitors of Uracil-DNA Glycosylase. Viruses 15 (6), ISSN 1999-4915.
Bagneris, Claire and Senthil Kumar, Swathi and Baratchian, M. and Britt, H. and Tufa, A. and Britt, H. and Thalassinos, Kostas and Collins, M. and Barrett, Tracey (2022) Mechanistic insights into the activation of the IKK kinase complex by the Kaposi’s Sarcoma Herpes virus oncoprotein vFLIP. Journal of Biological Chemistry 298 (6), p. 102012. ISSN 0021-9258.
Shyam, M. and Verma, H. and Bhattacharje, G. and Mukherjee, P. and Singh, S. and Kamilya, S. and Jalani, P. and Das, S. and Dasgupta, A. and Mondal, A. and Das, A.K. and Singh, A. and Brucoli, F. and Bagneris, Claire and Dickman, R. and Basavanakatti, V.N. and Naresh Babu, P. and Sankaran, V. and Dev, A. and Sinha, B.N. and Bhakta, Sanjib and Jayaprakash, V. (2022) Mycobactin analogues with excellent pharmacokinetic profile demonstrate potent antitubercular specific activity and exceptional efflux pump inhibition. Journal of Medicinal Chemistry 65 (1), pp. 234-256. ISSN 0022-2623.
Earl, Chris and Bagneris, Claire and Zeman, K. and Cole, Ambrose and Barrett, Tracey and Savva, Renos (2018) A structurally conserved motif in γ-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping. Nucleic Acids Research 46 (8), pp. 4286-4300. ISSN 0305-1048.
Briggs, L.C. and Chan, A.W.E. and Davis, C.A. and Whitelock, N. and Hotiana, H. and Baratchian, M. and Bagneris, Claire and Selwood, D. and Collins, M.K. and Barrett, Tracey (2017) IKKγ mimetic peptides block the resistance to apoptosis associated with KSHV infection. Journal of Virology 91 (23), e01170-17. ISSN 0022-538X.
Lee, Hyunah and Patschull, Anathe and Bagneris, Claire and Ryan, H. and Sanderson, C.M. and Ebrahimi, B. and Nobeli, Irene and Barrett, Tracey E. (2017) KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing. Nucleic Acids Research 45 (8), pp. 4756-4767. ISSN 0305-1048.
Baratchian, M. and Davis, C.A. and Shimizu, A. and Escors, D. and Bagneris, Claire and Barrett, Tracey E. and Collins, M.K. (2016) Distinct activation mechanisms of NF-κB regulator inhibitor of NF-κB Kinase (IKK) by isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP)*. Journal of Biological Chemistry 291 , pp. 7608-7620. ISSN 0021-9258.
Sula, Altin and DeCaen, P. and Naylor, Claire and Zanatta, G. and Bagneris, Claire and Clapham, D.E. and Pryde, D. and Wallace, Bonnie A. (2016) Sodium Channel/Ligand complex structures as a guide for rational drug design. Biophysical Journal 110 (3), 33a. ISSN 0006-3495.
Naylor, Claire and Bagneris, Claire and DeCaen, P.G. and Sula, A. and Scaglione, A. and Clapham, D.E. and Wallace, Bonnie A. (2016) Molecular basis of ion permeability in a voltage-gated sodium channel. Embo Journal 35 (8), pp. 820-830. ISSN 0261-4189.
Bagneris, Claire and Rogala, Kacper B. and Baratchian, M. and Zamfir, Vlad and Kunze, Micha B.A. and Dagless, S. and Pirker, K.F. and Collins, M.K. and Hall, B.A. and Barrett, Tracey E. and Kay, C.W.M. (2015) Probing the solution structure of IκB Kinase (IKK) Subunit γ and its interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting protein and IKK Subunit β by EPR spectroscopy. Journal of Biological Chemistry 290 (27), pp. 16539-16549. ISSN 0021-9258.
Bagneris, Claire and Naylor, Claire E. and McCusker, Emily C. and Wallace, Bonnie A. (2014) Structural model of the open-closed-inactivated cycle of prokaryotic voltage-gated sodium channels. The Journal of General Physiology 145 (1), pp. 5-16. ISSN 0022-1295.
Chauviac, Francois-Xavier and Robertson, Giles and Quay, Doris H.X. and Bagneris, Claire and Dumas, C. and Henderson, B. and Ward, J. and Keep, Nicholas H. and Cohen-Gonsaud, Martin (2014) RpfC (Rv1884) atomic structure shows high structural conservation within the resuscitation promoting factor catalytic domain. Acta Crystallographica Section F: Structural Biology Communications F70 (8), pp. 1022-1026. ISSN 1744-3091.
Bagneris, Claire and DeCaen, P.G. and Naylor, Claire E. and Pryde, D.C. and Nobeli, Irene and Clapham, D.E. and Wallace, Bonnie A. (2014) Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism. Proceedings of the National Academy of Sciences of the United States of America 111 (23), pp. 8428-8433. ISSN 0027-8424.
Bagneris, Claire and DeCaen, P.G. and Hall, B.A. and Naylor, Claire E. and Clapham, D.E. and Kay, C.W.M. and Wallace, Bonnie A. (2013) Role of the C-terminal domain in the structure and function of tetrameric sodium channels. Nature Communications 4 , p. 2465. ISSN 2041-1723.
Ulmschneider, Martin B. and Bagneris, Claire and McCusker, Emily C. and DeCaen, P.G. and Delling, M. and Clapham, D.E. and Ulmschneider, J.P. and Wallace, Bonnie A. (2013) Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel. Proceedings of the National Academy of Sciences of the United States of America 110 (16), pp. 6364-6369. ISSN 0027-8424.
Ulmschneider, Martin B. and Bagneris, Claire and McCusker, Emily C. and Ulmschneider, J.P. and Wallace, Bonnie A. (2013) Microsecond molecular dynamics simulations of the open state structure of a bacterial voltage-gated sodium channel reveal mechanisms of ion selectivity and conduction. Biophysical Journal 104 (2), 132a-133a. ISSN 0006-3495.
McCusker, Emily C. and Bagneris, Claire and Naylor, Claire E. and Cole, Ambrose R. and d'Avanzo, N. and Nichols, C.G. and Wallace, Bonnie A. (2012) Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing. Nature Communications 3 , ISSN 2041-1723.
Webster, Matthew P. and Jukes, R. and Zamfir, V.S. and Kay, Christopher W.M. and Bagneris, Claire and Barrett, Tracey E. (2012) Crystal structure of the UvrB dimer: insights into the nature and functioning of the UvrAB damage engagement and UvrB-DNA complexes. Nucleic Acids Research 40 (17), pp. 8743-8758. ISSN 0305-1048.
Baldwin, A.J. and Hilton, G.R. and Lioe, H. and Bagneris, Claire and Benesch, J.L.P. and Kay, L.E. (2011) Quaternary dynamics of αB-crystallin as a direct consequence of localised tertiary fluctuations in the C-terminus. Journal of Molecular Biology 413 (2), pp. 310-320. ISSN 0022-2836.
Bagneris, Claire and Briggs, Louise C. and Savva, Renos and Ebrahimi, B. and Barrett, Tracey E. (2011) Crystal structure of a KSHV-SOX-DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoff. Nucleic Acids Research 39 (13), pp. 5744-5756. ISSN 0305-1048.
Clark, Alice R. and Naylor, Claire E. and Bagneris, Claire and Keep, Nicholas H. and Slingsby, Christine (2011) Crystal structure of R120G disease mutant of human αB-Crystallin Domain Dimer shows closure of a groove. Journal of Molecular Biology 408 (1), pp. 118-134. ISSN 0022-2836.
Shimizu, A. and Baratchian, M. and Takeuchi, Y. and Escors, D. and MacDonald, D. and Barrett, Tracey E. and Bagneris, Claire and Collins, M. and Noursadeghi, M. (2011) Kaposi's Sarcoma-Associated Herpesvirus vFLIP and Human T Cell Lymphotropic Virus Type 1 Tax Oncogenic Proteins Activate I B Kinase Subunit by Different Mechanisms Independent of the Physiological Cytokine-Induced Pathways. Journal of Virology 85 (14), pp. 7444-7448. ISSN 0022-538X.
Bagneris, Claire and Bateman, Orval A. and Naylor, Claire E. and Cronin, Nora and Boelens, W.C. and Keep, Nicholas H. and Slingsby, Christine (2009) Crystal structures of α-Crystallin Domain Dimers of αB-Crystallin and Hsp20. Journal of Molecular Biology 392 (5), pp. 1242-1252. ISSN 0022-2836.
Bagneris, Claire and Ageichik, A.V. and Cronin, Nora and Wallace, Bonnie A. and Collins, M. and Boshoff, C. and Waksman, Gabriel and Barrett, Tracey E. (2008) Crystal structure of a vFlip-IKKγ Complex: insights into viral activation of the IKK Signalosome. Molecular Cell 30 (5), pp. 620-631. ISSN 1097-2765.
Bagneris, Claire and Ageichik, A.V. and Cronin, Nora and Wallace, Bonnie A. and Collins, M. and Boshoff, C. and Waksman, Gabriel and Barrett, Tracey E. (2008) Crystal structure of a vFlip-IKK gamma complex: Insights into viral activation of the IKK signalosome. Molecular Cell 30 (5), pp. 620-631. ISSN 1097-2765.
Cohen Gonsaud, M. and Barthe, P. and Bagneris, Claire and Henderson, B. and Ward, J.M. and Roumestand, C. and Keep, Nicholas H. (2005) The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes. Nature Structural and Molecular Biology 12 (3), pp. 270-273. ISSN 1545-9993.