A

Allen, William J. and Phan, Gilles and Waksman, Gabriel (2009) Structural biology of periplasmic chaperones. In: Eisenberg, D.S. and McPherson, A. (eds.) Advances in Protein Chemistry and Structural Biology. Maryland, U.S.: Academic Press Inc., pp. 51-98. ISBN 9780123748270.

B

Bagneris, Claire and Bateman, Orval A. and Naylor, Claire E. and Cronin, Nora and Boelens, W.C. and Keep, Nicholas H. and Slingsby, Christine (2009) Crystal structures of α-Crystallin Domain Dimers of αB-Crystallin and Hsp20. Journal of Molecular Biology 392 (5), pp. 1242-1252. ISSN 0022-2836.

Baran, K. and Dunstone, M.A. and Chia, J. and Ciccone, A. and Browne, K.A. and Clarke, C.J.P. and Lukoyanova, Natalya and Saibil, Helen R. and Whisstock, J.C. and Voskoboinik, I. and Trapani, J.A. (2009) The molecular basis for perforin oligomerization and transmembrane pore assembly. Immunity 30 (5), pp. 684-695. ISSN 1074-7613.

Bodey, Andrew J. and Kikkawa, M. and Moores, Carolyn A. (2009) 9-Angström structure of a microtubule-bound mitotic motor. Journal of Molecular Biology 388 (2), pp. 218-224. ISSN 0022-2836.

Bodey, Andrew J. and Kikkawa, M. and Moores, Carolyn A. (2009) The ATP state of a mitotic Kinesin-5 bound to microtubules. Biophysical Journal 96 (3(S1)), 215a-215a. ISSN 0006-3495.

C

Cabrita, L.D. and Hsu, S.T.D. and Launay, H. and Dobson, C.M. and Christodoulou, John (2009) Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America 106 (52), pp. 22239-22244. ISSN 0027-8424.

Carlomagno, F. and Guida, T. and Anaganti, S. and Provitera, L. and Kjaer, S. and McDonald, Neil Q. and Ryan, A.J. and Santoro, M. (2009) Identification of tyrosine 806 as a molecular determinant of RET kinase sensitivity to ZD6474. Endocrine-Related Cancer 16 (1), pp. 233-241. ISSN 1351-0088.

Chandran, Vidya and Duquerroy, S. and Cronin, Nora and Navaza, J. and Fronzes, Remi and Waksman, Gabriel (2009) Structure of the outer membrane complex of a type IV secretion system. Nature 462 (7276), pp. 1011-1015. ISSN 0028-0836.

Charalambous, Kalypso and O’Reilly, Andrias O. and Bullough, P.A. and Wallace, Bonnie A. (2009) Thermal and chemical unfolding and refolding of a eukaryotic sodium channel. Biochimica et Biophysica Acta (BBA) - Biomembranes 1788 (6), pp. 1279-1286. ISSN 0006-3002.

Christodoulou, John and Hsu, S.T.D. and Cabrita, L.D. and Fucini, P. and Dobson, C.M. (2009) Probing protein folding on the Ribosome by Solution State NMR Spectroscopy. Journal of Biomolecular Structure & Dynamics 26 (6), p. 94. ISSN 0739-1102.

Clare, Daniel K. and Bakkes, P.J. and van Heerikhuizen, H. and van der Vies, S.M. and Saibil, Helen R. (2009) Chaperonin complex with a newly folded protein encapsulated in the folding chamber. Nature (457), pp. 107-110. ISSN 0028-0836.

D

Drechsler, A. and Miles, Andrew J. and Norton, R.S. and Wallace, Bonnie A. and Separovic, F. (2009) Effect of lipid on the conformation of the N-terminal region of equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study. European Biophysics Journal with Biophysics letters 39 (1), pp. 121-127. ISSN 0175-7571.

Durand, E. and Verger, Denis and Rego, A.T. and Chandran, Vidya and Meng, G.Y. and Fronzes, Remi and Waksman, Gabriel (2009) Structural biology of bacterial secretion systems in gram-negative pathogens--potential for new drug targets. Infectious Disorders - Drug Targets 9 (5), pp. 518-847. ISSN 1871-5265.

E

Ekeowa, U.I. and Gooptu, Bibek and Belorgey, D. and Hägglöf, P. and Karlsson‑Li, S. and Miranda, E. and Pérez, J. and MacLeod, I. and Kroger, H. and Marciniak, S.J. and Crowther, D.C. and Lomas, D.A. (2009) α1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies. Clinical Science 116 (12), pp. 837-850. ISSN 0143-5221.

F

Fronzes, Remi and Christie, P.J. and Waksman, Gabriel (2009) The structural biology of type IV secretion systems. Nature Reviews Microbiology 7 (10), pp. 703-714. ISSN 1740-1526.

Fronzes, Remi and Schafer, Eva and Wang, Luchun and Saibil, Helen R. and Orlova, Elena and Waksman, Gabriel (2009) Structure of a type IV secretion system core complex. Science 323 (5911), pp. 266-268. ISSN 0036-8075.

G

Gooptu, Bibek and Ekeowa, U.I. and Lomas, D.A. (2009) Mechanisms of emphysema in 1-antitrypsin deficiency: molecular and cellular insights. European Respiratory Journal 34 (2), pp. 475-488. ISSN 0903-1936.

Gooptu, Bibek and Lomas, D.A. (2009) Conformational pathology of the serpins: themes, variations, and therapeutic strategies. Annual Review of Biochemistry 78 (1), pp. 147-176. ISSN 0066-4154.

Gooptu, Bibek and Miranda, E. and Nobeli, Irene and Mallya, M. and Purkiss, Andrew G. and Leigh Brown, S.C. and Summers, C. and Phillips, R.L. and Lomas, D.A. and Barrett, Tracey E. (2009) Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of α1-Antitrypsin: implications for disease and drug design. Journal of Molecular Biology 387 (4), pp. 857-868. ISSN 0022-2836.

Guenou, H. and Nissan, X. and Larcher, F. and Feteira, J. and Lemaître, G. and Saidani, M. and Del Rio, M. and Barrault, C.C. and Bernard, F.-X. and Peschanski, M. and Baldeschi, C. and Waksman, Gabriel (2009) Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study. The Lancet 374 (9703), pp. 1745-1753. ISSN 0140-6736.

Gupta, Antima and Bhakta, Sanjib and Kundu, S. and Gupta, M. and Srivastava, B.S. and Srivastava, R. (2009) Fast-growing, non-infectious and intracellularly surviving drug resistant Mycobacterium aurum: a model for high-throughput antituberculosis drug screening. Journal of Antimicrobial Chemotherapy 64 (4), pp. 774-781. ISSN 0305-7453.

H

Halling-Brown, Mark D. and Moss, David S. and Sansom, Clare E. and Shepherd, Adrian J. (2009) A computational grid framework for immunological applications. Philosophical Transactions of the Royal Society A 367 (1898), pp. 2705-2716. ISSN 1364-503X.

Halling-Brown, Mark D. and Shaban, R. and Frampton, D. and Sansom, Clare E. and Davies, M.N. and Flower, D.R. and Duffield, M. and Titball, R.W. and Brusic, V. and Moss, David S. (2009) Proteins accessible to immune surveillance show significant T-cell epitope depletion: implications for vaccine design. Molecular Immunology 46 (13), pp. 2699-2705. ISSN 0161-5890.

Hayward, Richard D. and Hume, P.J. and Humphreys, D. and Phillips, N. and Smith, K. and Koronakis, V. (2009) Clustering transfers the translocatedEscherichia colireceptor into lipid rafts to stimulate reversible activation of c-Fyn. Cellular Microbiology 11 (3), pp. 433-441. ISSN 1462-5814.

Hsu, S.T.D. and Cabrita, L.D. and Christodoulou, John and Dobson, C.M. (2009) H-1, N-15 and C-13 assignments of domain 5 of Dictyostelium discoideum gelation factor (ABP-120) in its native and 8M urea-denatured states. Biomolecular Nmr Assignments 3 (1), pp. 29-31. ISSN 1874-2718.

Hsu, S.T.D. and Cabrita, L.D. and Fucini, P. and Christodoulou, John and Dobson, C.M. (2009) Probing side-chain dynamics of a ribosome-bound nascent chain using methyl NMR spectroscopy. Journal of the American Chemical Society 131 (24), pp. 8366-8367. ISSN 0002-7863.

Hsu, S.T.D. and Cabrita, L.D. and Fucini, P. and Dobson, C.M. and Christodoulou, John (2009) Structure, dynamics and folding of an Immunoglobulin Domain of the Gelation Factor (ABP-120) from Dictyostelium discoideum. Journal of Molecular Biology 388 (4), pp. 865-879. ISSN 0022-2836.

Hultgren, S.J. and Waksman, Gabriel (2009) Structural biology of the chaperone-usher pathway of pilus biogenesis. Nature Reviews Microbiology 7 , pp. 765-774. ISSN 1740-1526.

J

Jakubowski, S.J. and Kerr, J.E. and Garza, I. and Krishnamoorthy, V. and Bayliss, R. and Waksman, Gabriel and Christie, P.J. (2009) Agrobacterium VirB10 domain requirements for type IV secretion and T pilus biogenesis. Molecular Microbiology 71 (3), pp. 779-794. ISSN 0950-382X.

K

Kabiljo, R. and Clegg, A.B. and Shepherd, Adrian J. (2009) A realistic assessment of methods for extracting gene/protein interactions from free text. BMC Bioinformatics 10 , p. 233. ISSN 1471-2105.

Kenjale, R. and Fink, D.L. and Juehne, T. and Ohashi, T. and Erickson, H.P. and Meng, G.Y. and Waksman, Gabriel and St. Geme, J.W. (2009) Structural determinants of autoproteolysis of the Haemophilus influenzae Hap autotransporter. Infection and Immunity 77 (11), pp. 4704-4713. ISSN 0019-9567.

King, M.D. and Rennie, A.R. and Thompson, Katherine C. and Fisher, F.N. and Dong, C.C. and Thomas, R.K. and Pfrang, C. and Hughes, A.V. (2009) Oxidation of oleic acid at the air-water interface and its potential effects on cloud critical supersaturations. Physical Chemistry Chemical Physics 11 (35), pp. 7699-7707. ISSN 1463-9076.

Kostelecky, B. and Saurin, A.T. and Purkiss, Andrew G. and Parker, P.J. and McDonald, Neil Q. (2009) Recognition of an intra-chain tandem 14-3-3 binding site within PKCepsilon. EMBO Reports 10 (9), pp. 983-989. ISSN 1469-3178.

L

Lasker, K. and Topf, Maya and Sali, A. and Wolfson, H.J. (2009) Inferential optimization for simultaneous fitting of multiple components into a CryoEM map of their assembly. Journal of Molecular Biology 388 (1), pp. 180-184. ISSN 0022-2836.

Leary, J.A. and Schenauer, M.R. and Stefanescu, R. and Andaya, A. and Ruotolo, B.T. and Robinson, C.V. and Thalassinos, Konstantinos and Scrivens, J.H. and Sokabe, M. and Hershey, J.W.B. (2009) Methodology for measuring conformation of solvent-disrupted protein subunits using T-WAVE ion mobility MS: an investigation into eukaryotic initiation factors. Journal of the American Society for Mass Spectrometry 20 (9), pp. 1699-1706. ISSN 1044-0305.

Lendel, C. and Bertoncini, C.W. and Cremades, N. and Waudby, Christopher A. and Vendruscolo, M. and Dobson, C.M. and Schenk, D. and Christodoulou, John and Toth, G. (2009) On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of α-synuclein with congo red and lacmoid. Biochemistry 48 (35), pp. 8322-8334. ISSN 0006-2960.

Lhuillier, S. and Gallopin, M. and Gilquin, B. and Brasiles, S. and Lancelot, N. and Letellier, G. and Gilles, M. and Dethan, G. and Orlova, Elena and Couprie, J. and Tavares, P. and Zinn-Justin, S. (2009) Structure of bacteriophage SPP1 head-to-tail connection reveals mechanism for viral DNA gating. Proceedings of the National Academy of Sciences of the United States of America 106 (21), pp. 8507-8512. ISSN 0027-8424.

Loakes, D. and Gallego, J. and Pinheiro, Vitor B. and Kool, Eric T. and Holliger, Philipp (2009) Evolving a polymerase for hydrophobic base analogues. Journal of the American Chemical Society 131 (41), pp. 14827-14837. ISSN 0002-7863.

M

Macchiarulo, A. and Thornton, Janet M. and Nobeli, Irene (2009) Mapping human metabolic pathways in the small molecule chemical space. Journal of Chemical Information and Modelling 49 (10), pp. 2272-2289. ISSN 1549-9596.

McCusker, Emily C. and Wallace, Bonnie A. (2009) Expression, purification and biophysical characterization of a superfamily of prokaryotic voltage-gated sodium channels. Biophysical Journal 96 (3(S1)), 13a-13a. ISSN 0006-3495.

Meng, G.Y. and Chandran, Vidya and Remaut, Han and Fronzes, Remi and Waksman, Gabriel (2009) Protein oligomerization in the bacterial outer membrane (Review). Molecular Membrane Biology 26 (3), pp. 136-145. ISSN 0968-7688.

Mirkin, Boris and Gutman, P.O. (2009) Adaptive output-feedback tracking: the case of MIMO plants with unknown, time-varying state delay. Systems & Control Letters 58 (1), pp. 62-68. ISSN 0167-6911.

Mirkin, Boris and Levene, Mark (2009) Special issue on profiling expertise and behaviour. Computer Journal 52 (7), pp. 727-728. ISSN 0010-4620.

Mulder, A.M. and Glavis-Bloom, A. and Moores, Carolyn A. and Wagenbach, M. and Carragher, B. and Wordeman, L. and Milligan, R.A. (2009) A new model for binding of kinesin 13 to curved microtubule protofilaments. Journal of Cell Biology 185 (1), pp. 51-57. ISSN 0021-9525.

N

Nilapwar, S. and Smith, E.P. and Fu, C. and Prodromou, C. and Pearl, L.H. and Williams, Mark A. and Ladbury, J.E. (2009) Structural-thermodynamics relationships of interactions in the N-terminal ATP binding domain of Hsp90. Journal of Molecular Biology 392 (4), pp. 923-936. ISSN 0022-2836.

Nilapwar, S. and Williams, E. and Fu, C. and Prodromou, C. and Pearl, L.H. and Williams, Mark A. and Ladbury, J.E. (2009) Structural–thermodynamic relationships of interactions in the N-Terminal ATP-Binding domain of Hsp90. Journal of Molecular Biology 392 (4), pp. 923-936. ISSN 0022-2836.

Nobeli, Irene and Favia, A.D. and Thornton, Janet M. (2009) Protein promiscuity and its implications for biotechnology. Nature Biotechnology 27 , pp. 157-167. ISSN 1087-0156.

O

Okorokov, A.L. and Orlova, Elena (2009) Structural biology of the p53 tumour suppressor. Current Opinion in Structural Biology 19 (2), pp. 197-202. ISSN 0959-440X.

Orlova, Elena (2009) How viruses infect bacteria? Embo Journal 28 , pp. 797-798. ISSN 0261-4189.

O’Donnell, G. and Poeschl, R. and Zimhony, O. and Gunaratnam, M. and Moreira, J.B.C. and Neidle, S. and Evangelopoulos, Dimitrios and Bhakta, Sanjib and Malkinson, J. and Boshoff, H.I. and Lenaerts, A. and Gibbons, S. (2009) Bioactive Pyridine-N-oxide Disulfides from Allium stipitatum. Journal of Natural Products 72 (3), pp. 360-365. ISSN 0163-3864.

O’Reilly, Andrias O. and Charalambous, Kalypso and Nurani, G. and Wallace, Bonnie A. (2009) Design, production and characterisation of a thermally-stable mutant of the bacterial voltage gated sodium channel Nachbac. Biophysical Journal 96 (3(S1)), 253a-253a. ISSN 0006-3495.

O’Reilly, Andrias O. and Davies, T.G.E. and Usherwood, P.N.R. and Mellor, I. and Williamson, M.S. and Field, L.M. and Wallace, Bonnie A. (2009) Insecticide binding to voltage-gated sodium channels. Biophysical Journal 96 (3(S1)), 14a-14a. ISSN 0006-3495.

P

Pappalardo, F. and Halling-Brown, Mark D. and Rapin, N. and Zhang, P. and Alemani, D. and Emerson, A. and Paci, P. and Duroux, P. and Pennisi, M. and Palladini, A. and Miotto, O. and Churchill, D. and Rossi, E. and Shepherd, Adrian J. and Moss, David S. and Castiglione, F. and Bernaschi, M. and Lefranc, M.P. and Brunak, S. and Motta, S. and Lollini, P.L. and Basford, K.E. and Brusic, V. (2009) ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization. Briefings in Bioinformatics 10 (3), pp. 330-340. ISSN 1467-5463.

Patel, V.J. and Thalassinos, Konstantinos and Slade, S.E. and Connolly, J.B. and Crombie, A. and Murrell, J.C. and Scrivens, J.H. (2009) A comparison of labeling and label-free Mass Spectrometry-based Proteomics approaches. Journal of Proteome Research 8 (7), pp. 3752-3759. ISSN 1535-3893.

Perrone, B. and Miles, Andrew J. and Bechinger, B. and Vrønning Hoffmann, S. and Wallace, Bonnie A. (2009) Oriented synchrotron radiation circular dichroism and linear dichroism spectroscopy of peptides in model membranes. Biophysical Journal 96 (3(S1)), 337a-337a. ISSN 0006-3495.

Powl, Andrew M. and Wallace, Bonnie A. (2009) Chimeric bacterial-human NaV17 sodium channels expressed in E coli. Biophysical Journal 96 (3(S1)), 13a-13a. ISSN 0006-3495.

R

Radin, J.N. and Grass, S.A. and Meng, G.Y. and Cotter, S.E. and Waksman, Gabriel and St. Geme, J.W. (2009) Structural basis for the differential binding affinities of the HsfBD1 and HsfBD2 domains in the Haemophilus influenzae Hsf adhesin. Journal of Bacteriology 191 (16), pp. 5068-5075. ISSN 0021-9193.

Rey, F.A. and Saibil, Helen R. (2009) Macromolecular assemblies. Current Opinion in Structural Biology 19 (2), pp. 178-180. ISSN 0959-440X.

Rivers, R.C. and Kumita, J.R. and Tartaglia, G.G. and Dedmon, M.M. and Pawar, A. and Vendruscolo, M. and Dobson, C.M. and Christodoulou, John (2009) Molecular determinants of the aggregation behavior of α- and β-synuclein. Protein Science 17 (5), pp. 887-898. ISSN 0961-8368.

Roffey, J. and Rosse, C. and Linch, M. and Hibbert, A. and McDonald, Neil Q. and Parker, P.J. (2009) Protein kinase C intervention: the state of play. Current Opinion in Cell Biology 21 (2), pp. 268-279. ISSN 1879-0410.

Romain, F. and Barbosa, I. and Gouge, Jerome and Rougeon, F. and Delarue, M. (2009) Conferring a template-dependent polymerase activity to terminal deoxynucleotidyltransferase by mutations in the Loop1 region. Nucleic Acids Research 37 (14), pp. 4642-56. ISSN 0305-1048.

S

Scarff, C.A. and Patel, V.J. and Thalassinos, Konstantinos and Scrivens, J.H. (2009) Probing hemoglobin structure by means of traveling-wave ion mobility mass spectrometry. Journal of the American Society for Mass Spectrometry 20 (4), pp. 625-631. ISSN 1044-0305.

Siddiqui, R. and Syed, A. and Tomas, Salvador and Prieto-Garcia, J. and Khan, Naveed Ahmed (2009) Effect of free versus liposomal-complexed pentamidine isethionate on biological characteristics of Acanthamoeba castellanii in vitro. Journal of Medical Microbiology 58 , pp. 327-330. ISSN 0022-2615.

Sulimova, V. and Mottl, V. and Mirkin, Boris and Muchnik, I. and Kulikowski, C. (2009) A class of evolution-based kernels for protein homology analysis: a generalization of the PAM model. In: Măndoiu, I. and Narasimhan, G. and Zhang, Y. (eds.) Bioinformatics Research and Applications. Lecture Notes in Computer Science 5542. Berlin, Germany: Springer Verlag, pp. 284-296. ISBN 9783642015502.

T

Tarry, M.J. and Schafer, Eva and Chen, S.Y. and Buchanan, G. and Greene, N.P. and Lea, S.M. and Palmer, T. and Saibil, Helen R. and Berks, B.C. (2009) Structural analysis of substrate binding by the TatBC component of the twin-arginine protein transport system. Proceedings of the National Academy of Sciences of the United States of America 106 (32), pp. 13284-13289. ISSN 0027-8424.

Taylor, D.J. and Devkota, B. and Huang, A.D. and Topf, Maya and Narayanan, E. and Sali, A. and Harvey, S.C. and Frank, J. (2009) Comprehensive molecular structure of the Eukaryotic Ribosome. Structure 17 (12), pp. 1591-1604. ISSN 0969-2126.

Thalassinos, Konstantinos and Grabenauer, M. and Slade, S.E. and Hilton, G.R. and Bowers, M.T. and Scrivens, J.H. (2009) Characterization of phosphorylated peptides using traveling wave-based and drift cell ion mobility mass spectrometry. Analytical Chemistry 81 (1), pp. 248-254. ISSN 0003-2700.

Tomas, Salvador (2009) Bioinspired organic chemistry. Annual Reports on the Progress of Chemistry - Section B 105 , pp. 440-463. ISSN 0069-3030.

Tomas, Salvador and Milanesi, Lilia (2009) Hydrophobically self-assembled nanoparticles as molecular receptors in water. Journal of the American Chemical Society 131 (18), pp. 6618-6623. ISSN 0002-7863.

V

Vaughan, Cara K. and Piper, P.W. and Pearl, L.H. and Prodromou, C. (2009) A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s. FEBS Journal 276 (1), pp. 199-209. ISSN 1742-464X.

Vuchelen, A. and O’Day, E. and de Genst, E. and Pardon, E. and Lode Wyns, L. and Dobson, C.M. and Christodoulou, John and Hsu, S.T.D. (2009) 1H, 13C and 15N assignments of a camelid nanobody directed against human α-synuclein. Biomolecular Nmr Assignments 3 (2), pp. 231-233. ISSN 1874-2718.

W

Waksman, Gabriel (2009) Going round in circles: the structural biology of type III secretion systems. Nature Structural & Molecular Biology 16 , pp. 459-460. ISSN 1545-9985.

Waksman, Gabriel and Hultgren, S.J. (2009) Structural biology of the chaperone–usher pathway of pilus biogenesis. Nature Reviews Microbiology 7 (11), pp. 765-774. ISSN 1740-1526.

Wallace, Bonnie A. (2009) Protein characterisation by synchrotron radiation circular dichroism spectroscopy. Quarterly Reviews of Biophysics 42 (4), pp. 317-370. ISSN 0033-5835.

Wallace, Bonnie A. and Janes, R.W. (2009) Modern techniques for circular dichroism and synchrotron radiation circular dichroism spectroscopy: 1. Advances in Biomedical Spectroscopy. Amsterdam, The Netherlands: IOS Press. ISBN 9781607500001.

Wendler, Petra and Shorter, J. and Snead, D. and Plisson, Celia and Clare, Daniel K. and Lindquist, S. and Saibil, Helen R. (2009) Motor mechanism for protein threading through Hsp104. Molecular Cell 34 (1), pp. 81-92. ISSN 1097-2765.

White, Helen E. and Hodgkinson, J.L. and Jahn, T.R. and Cohen-Krausz, Sara and Gosal, W.S. and Muller, S. and Orlova, Elena and Radford, S.E. and Saibil, Helen R. (2009) Globular Tetramers of beta(2)-Microglobulin assemble into elaborate amyloid fibrils. Journal of Molecular Biology 389 (1), pp. 48-57. ISSN 0022-2836.

Z

Zhou, J.J. and Robertson, Giles and He, X. and Dufour, S. and Hooper, A.M. and Pickett, J.A. and Keep, Nicholas H. and Field, L.M. (2009) Characterisation of Bombyx mori odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components. Journal of Molecular Biology 389 (3), pp. 529-545. ISSN 0022-2836.