Browse by Staff

Hollingworth, Dave and Thomas, Frances and Page, D.A. and Fouda, M.A. and Lopez-Rios De Castro, R. and Sula, A. and Mykhaylyk, V.B. and Kelly, G. and Ulmschneider, M.B. and Ruben, P.C. and Wallace, Bonnie (2024) Structural basis for the rescue of hyperexcitable cells by the amyotrophic lateral sclerosis drug Riluzole. Nature Communications 15 (1), p. 8426. ISSN 2041-1723.

Ramalli, S.G. and Miles, Andrew and Janes, R.W. and Wallace, Bonnie A. (2022) The PCDDB (Protein Circular Dichroism Data Bank): a bioinformatics resource for protein characterisations and methods development. Journal of Molecular Biology 434 (11), p. 167441. ISSN 0022-2836.

D’Avanzo, N. and Miles, Andrew and Powl, Andrew and Nichols, C.G. and Wallace, Bonnie A. and O'Reilly, Andrias (2022) The T1-tetramerization domain of Kv1.2 rescues expression and preserves function of a truncated NaChBac Sodium Channel. FEBS Letters 596 (6), pp. 772-783. ISSN 1873-3468.

Miles, Andrew and Janes, R.W. and Wallace, Bonnie A. (2021) Tools and methods for Circular Dichroism Spectroscopy of proteins. Chemical Society Reviews 50 (15), pp. 8400-8413. ISSN 0306-0012.

Groves, K. and Ashcroft, A.E. and Cryar, A. and Sula, A. and Wallace, Bonnie A. and Stocks, B. B. and Burns, C. and Cooper-Shepherd, D. and De Lorenzi, E. and Rodriguez, E. and Zhang, H. and Ault, J.R. and Ferguson, J. and Phillips, J.J. and Pacholarz, K. and Thalassinos, K. and Luckau, L. and Ashton, L. and Durrant, O. and Barran, P. and Dalby, P. and Vicedo, P. and Colombo, R. and Davis, R. and Parakra, R. and Upton, R. and Hill, S. and Wood, V. and Soloviev, Z. and Quaglia, M. (2021) Reference protocol to assess analytical performance of higher order structural analysis measurements: results from an interlaboratory comparison. Analytical Chemistry 93 (26), pp. 9041-9048. ISSN 0003-2700.

Sula, A. and Hollingworth, D. and Ng, L.C.T. and Larmore, M. and DeCaen, P.G. and Wallace, Bonnie A. (2021) A tamoxifen receptor within a voltage-gated sodium channel. Molecular Cell 81 (6), pp. 1160-1169. ISSN 1097-2765.

Sait, L.G. and Sula, A. and Ghovanloo, M.-R. and Hollingworth, D. and Ruben, P.C. and Wallace, Bonnie A. (2020) Cannabidiol interactions with voltage-gated sodium channels. eLife 9 , ISSN 2050-084X.

Felizatti, A.P. and Zeraik, A.E. and Basso, L.G.M. and Kumagai, P.S. and Lopes, J.L.S. and Wallace, Bonnie A. and Araujo, A.P.U. and DeMarco, R. (2019) Interactions of amphipathic α-helical MEG proteins from Schistosoma mansoni with membranes. Biochimica et Biophysica Acta (BBA) - Biomembranes 1862 (3), p. 183173. ISSN 0005-2736.

Davey, N.E. and Babu, M.M. and Blackledge, M. and Bridge, A. and Capella-Gutierrez, S. and Dosztanyi, Z. and Drysdale, R. and Edwards, R.J. and Elofsson, A. and Felli, I.C. and Gibson, T.J. and Gutmanas, A. and Hancock, J.M. and Harrow, J. and Higgins, D. and Jeffries, C.M. and Le Mercier, P. and Mészáros, B. and Necci, M. and Notredame, C. and Orchard, S. and Ouzounis, C.A. and Pancsa, R. and Papaleo, E. and Pierattelli, R. and Piovesan, D. and Promponas, V.J. and Ruch, P. and Rustici, G. and Romero, P. and Sarntivijai, S. and Saunders, G. and Schuler, B. and Sharan, M. and Shields, D.C. and Sussman, J.L. and Tedds, J.A. and Tompa, P. and Turewicz, M. and Vondrasek, J. and Vranken, W.F. and Wallace, Bonnie A. and Wichapong, K. and Tosatto, S.C.E. (2019) An intrinsically disordered proteins community for ELIXIR. F1000Research 8 , p. 1753. ISSN 2046-1402.

Wallace, Bonnie A. (2019) The role of Circular Dichroism Spectroscopy in the era of integrative structural biology. Current Opinion in Structural Biology 58 , pp. 191-196. ISSN 0959-440X.

Kumagai, P.S. and Sousa, V.K. and Donato, M. and Itri, R. and Beltramini, L.M. and Araujo, A.P.U. and Buerck, J. and Wallace, Bonnie A. and Lopes, J.L.S. (2019) Unveiling the binding and orientation of the antimicrobial peptide Plantaricin 149 in zwitterionic and negatively charged membranes. European Biophysics Journal 48 , pp. 621-633. ISSN 0175-7571.

Ke, S. and Ulmschneider, M.B. and Wallace, Bonnie A. and Ulmschneider, J.P. (2018) Role of the Interaction Motif in Maintaining the Open Gate of an Open Sodium Channel. Biophysical Journal 115 (10), pp. 1920-1930. ISSN 0006-3495.

Ireland, Sam and Sula, Altin and Wallace, Bonnie A. (2018) Thermal melt circular dichroism spectroscopic studies for identifying stabilising amphipathic molecules for the voltage-gated sodium channel NavMs. Biopolymers 109 (8), e23067. ISSN 0006-3525.

Miles, Andrew J. and Wallace, Bonnie A. (2018) CDtoolX, a downloadable software package for processing and analyses of Circular Dichroism Spectroscopic Data. Protein Science 27 (9), pp. 1717-1722. ISSN 0961-8368.

Kumagai, P.S. and Gutierrez, R.F. and Lopes, J.L.S. and Martins, J.M. and Jameson, D.M. and Castro, A.M. and Martins, L.F. and DeMarco, R. and Bossolan, N.R.S. and Wallace, Bonnie A. and Araujo, A.P.U. (2018) Characterization of esterase activity from an Acetomicrobium hydrogeniformans enzyme with high structural stability in extreme conditions. Extremophiles 22 (5), pp. 781-793. ISSN 1431-0651.

Liko, I. and Degiacomi, M.T. and Lee, S. and Newport, T.D. and Gault, J. and Reading, E. and Hopper, J.T.S. and Housden, N.G. and White, P. and Colledge, M. and Sula, Altin and Wallace, Bonnie A. and Kleanthous, C. and Stansfeld, P.J. and Bayley, H. and Benesch, J.L.P. and Allison, T.M. and Robinson, C.V. (2018) Lipid binding attenuates channel closure of the outer membrane protein OmpF. Proceedings of the National Academy of Sciences of the United States of America , ISSN 0027-8424.

Tolchard, J. and Walpole, S.J. and Miles, Andrew J. and Maytum, R. and Eaglen, L.A. and Hackstadt, T. and Wallace, Bonnie A. and Blumenschein, T.M.A. (2018) The intrinsically disordered Tarp protein from chlamydia binds actin with a partially preformed helix. Scientific Reports 8 (1), p. 1960. ISSN 2045-2322.

Whitmore, L. and Mavridis, L. and Wallace, Bonnie A. and Janes, R.W. (2018) DichroMatch at the Protein Circular Dichroism Data Bank (DM@PCDDB): a web-based tool for identifying protein nearest neighbors using Circular Dichroism Spectroscopy. Protein Science 27 (1), pp. 10-13. ISSN 0961-8368.

O’Reilly, A.O. and Lattrell, A. and Miles, Andrew J. and Klinger, A.B. and Nau, C. and Wallace, Bonnie A. and Lampert, A. (2017) Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine. European Biophysics Journal 46 (7), pp. 665-674. ISSN 0175-7571.

Field, L.M. and Emyr Davies, T.G. and O’Reilly, A.O. and Williamson, M.S. and Wallace, Bonnie A. (2017) Voltage-gated sodium channels as targets for pyrethroid insecticides. European Biophysics Journal with Biophysics letters 46 (7), pp. 675-679. ISSN 0175-7571.

Sula, Altin and Wallace, Bonnie A. (2017) Interpreting the functional role of a novel interaction motif in prokaryotic sodium channels. The Journal of General Physiology 149 (6), pp. 613-622. ISSN 0022-1295.

Yoneda, J.S. and Miles, Andrew J. and Araujo, A.P.U. and Wallace, Bonnie A. (2017) Differential dehydration effects on globular proteins and intrinsically disordered proteins during film formation. Protein Science 26 (4), pp. 718-726. ISSN 0961-8368.

Sula, Altin and Booker, Jennifer and Ng, L.C.T. and Naylor, Claire and DeCaen, P.G. and Wallace, Bonnie A. (2017) The complete structure of an activated open sodium channel. Nature Communications 8 , p. 14205. ISSN 2041-1723.

McDonald, C. and Jovanovic, G. and Wallace, Bonnie A. and Ces, O. and Buck, M. (2017) Structure and function of PspA and Vipp1 N-terminal peptides: Insights into the membrane stress sensing and mitigation. Biochimica et Biophysica Acta (BBA) - Biomembranes 1859 (1), pp. 28-39. ISSN 0005-2736.

Colledge, Matthew and Wallace, Bonnie A. (2016) AnglerFish: a webserver for defining the geometry of α-Helices in membrane proteins. Bioinformatics , btw781. ISSN 1367-4803.

Chin, S. and Yang, D. and Miles, Andrew J. and Eckford, P.D.W. and Molinski, S. and Wallace, Bonnie A. and Bear, C.E. (2016) Attenuation of Phosphorylation-dependent activation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by disease-causing mutations at the transmission interface. Journal of Biological Chemistry 292 (5), pp. 1988-1999. ISSN 0021-9258.

Orcia, D. and Zeraik, A.E. and Lopes, J.L.S. and Macedo, J.N.A. and Santos, C.R.d. and Oliveira, K.C. and Anderson, L. and Wallace, Bonnie A. and Verjovski-Almeida, S. and Araujo, A.P.U. and DeMarco, R. (2016) Interaction of an esophageal MEG protein from schistosomes with a human S100 protein involved in inflammatory response. Biochimica et Biophysica Acta (BBA) - General Subjects 1861 (1A), pp. 3490-3497. ISSN 0304-4165.

Whitmore, Lee and Miles, Andrew J. and Mavridis, L. and Janes, R.W. and Wallace, Bonnie A. (2016) PCDDB: new developments at the Protein Circular Dichroism Data Bank. Nucleic Acids Research 45 (D1), D303-D307. ISSN 0305-1048.

D'Auria, S. and Lopes, J.L.S. and Yoneda, Juliana and Martins, J.M. and DeMarco, R. and Jameson, D.M. and Castro, A.M. and Bossolan, N.R.S. and Wallace, Bonnie A. and Araujo, A.P.U. (2016) Environmental factors modulating the stability and enzymatic activity of the Petrotoga mobilis Esterase (PmEst). PLoS One 11 (6), e0158146. ISSN 1932-6203.

Miles, Andrew J. and Wallace, Bonnie A. (2016) Circular dichroism spectroscopy of membrane proteins. Chemical Society Reviews 18 , pp. 4859-4872. ISSN 0306-0012.

Miller, Wayne and Miles, Andrew J. and Wallace, Bonnie A. (2016) Structure of the C-terminal domain of the Prokaryotic Sodium Channel Orthologue NsvBa. European Biophysics Journal with Biophysics letters 45 (8), pp. 807-814. ISSN 0175-7571.

Drew, Elliott and Jones, D.T. and Wallace, Bonnie A. (2016) Protein design for decreased disorder: SHERP as an exemplar protein. Biophysical Journal 110 (3), 555a. ISSN 0006-3495.

Sula, Altin and DeCaen, P. and Naylor, Claire and Zanatta, G. and Bagneris, Claire and Clapham, D.E. and Pryde, D. and Wallace, Bonnie A. (2016) Sodium Channel/Ligand complex structures as a guide for rational drug design. Biophysical Journal 110 (3), 33a. ISSN 0006-3495.

Lopes, J.L.S. and Miles, A.J. and Whitmore, L. and Wallace, Bonnie A. (2016) Spectral properties of “Disordered” and Polyproline II structures defined by Circular Dichroism Spectroscopy. Biophysical Journal 110 (3), 559a-560a. ISSN 0006-3495.

Naylor, Claire and Bagneris, Claire and DeCaen, P.G. and Sula, A. and Scaglione, A. and Clapham, D.E. and Wallace, Bonnie A. (2016) Molecular basis of ion permeability in a voltage-gated sodium channel. Embo Journal 35 (8), pp. 820-830. ISSN 0261-4189.

Penny, C.J. and Rahman, T. and Sula, A. and Miles, A.J. and Wallace, Bonnie A. and Patel, S. (2016) Isolated pores dissected from human two-pore channel 2 are functional. Scientific Reports 6 , p. 38426. ISSN 2045-2322.

Ke, S. and Wallace, Bonnie A. and Ulmschneider, J.P. and Ulmschneider, M.B. (2016) Molecular dynamics simulations of the open state structure of a Bacterial Voltage-Gated Sodium Channel reveal the binding mechanisms of channel blockers. Biophysical Journal 110 (3), 108a. ISSN 0006-3495.

Evans, P. and Wyatt, K. and Wistow, G.J. and Bateman, O.A. and Wallace, Bonnie A. and Slingsby, Christine (2004) The P23T cataract mutation causes loss of solubility of folded γD-crystallin. Journal of Molecular Biology 343 (2), pp. 435-444. ISSN 0022-2836.