Arylamine N-acetyltransferases in Health and Disease

Evangelopoulos, Dimitrios and Bhakta, Sanjib (2018) Arylamine N-Acetyltransferase in Mycobacteria. In: Laurieri, N. and Sim, E. (eds.) Arylamine N-acetyltransferases in Health and Disease: From Pharmacogenetics to Drug Discovery and Diagnostics. World Scientific, pp. 303-324. ISBN 9789813232006.

BMJ Open

Guzman, Juan D. and Evangelopoulos, Dimitrios and Gupta, Antima and Birchall, K. and Mwaigwisya, S. and Saxty, B. and McHugh, T.D. and Gibbons, S. and Malkinson, J. and Bhakta, Sanjib (2013) Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay. BMJ Open 3 (6), e002672. ISSN 2044-6055.

Bioorganic & Medicinal Chemistry

McGuigan, C. and Derudas, M. and Gonczy, B. and Hinsinger, K. and Kandil, S. and Pertusati, F. and Serpi, M. and Snoeck, R. and Andrei, G. and Balzarini, J. and McHugh, T.D. and Maitra, A. and Akorli, E. and Evangelopoulos, Dimitrios and Bhakta, Sanjib (2014) ProTides of N–(3-(5-(2’-deoxyuridine))prop-2- ynyl)octanamide as potential anti-tubercular and anti-viral agents. Bioorganic & Medicinal Chemistry 22 (9), pp. 2816-2824. ISSN 1464-3391.

British Journal of Pharmacology

Ryan, A. and Polycarpou, E. and Lack, N.A. and Evangelopoulos, Dimitrios and Sieg, C. and Halman, A. and Bhakta, Sanjib and Eleftheriadou, O. and McHugh, T.D. and Keany, S. and Lowe, E.D. and Ballet, R. and Abuhammad, A. and Jacobs, W.R. and Ciulli, A. and Sim, E. (2017) Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach. British Journal of Pharmacology 174 (14), pp. 2209-2224. ISSN 0007-1188.

British Medical Bulletin

Maitra, Arundhati and Bhakta, Sanjib and Evangelopoulos, Dimitrios (2016) Repurposing drugs for treatment of tuberculosis (TB): a role for non-steroidal anti-inflammatory drugs. British Medical Bulletin 118 (1), pp. 138-148. ISSN 1471-8391.

Maitra, Arundhati and Bates, S. and Shaik, M. and Evangelopoulos, Dimitrios and Abubakar, I. and McHugh, T.D. and Lipman, M. and Bhakta, Sanjib (2016) Repurposing drugs for treatment of tuberculosis: a role for non-steroidal anti-inflammatory drugs. British Medical Bulletin 118 (1), pp. 138-148. ISSN 1471-8391.

Current Drug Metabolism

Sim, E. and Sandy, J. and Evangelopoulos, Dimitrios and Fullam, E. and Bhakta, Sanjib and Westwood, I.M. and Krylova, A. and Lack, N. and Noble, M. (2008) Arylamine N-acetyltransferases in mycobacteria. Current Drug Metabolism 9 (6), pp. 510-519. ISSN 1389-2002.

FEBS Journal

Evangelopoulos, Dimitrios and Cronin, Nora and Daviter, Tina and Sim, E. and Keep, Nicholas H. and Bhakta, Sanjib (2011) Characterization of an oxidoreductase from the arylamine N-acetyltransferase operon in Mycobacterium Smegmatis. FEBS Journal 278 (24), pp. 4824-4832. ISSN 1742-464X.

International Journal of Antimicrobial Agents

Shiu, W.K.P. and Malkinson, J.P. and Rahman, M.M. and Curry, J. and Stapleton, P. and Gunaratnam, M. and Neidle, S. and Mushtaq, S. and Warner, M. and Livermore, D.M. and Evangelopoulos, Dimitrios and Basavannacharya, Chandrakala and Bhakta, Sanjib and Schindler, B.D. and Seo, S.M. and Coleman, D. and Kaatz, G.W. and Gibbons, S. (2013) A new plant-derived antibacterial is an inhibitor of efflux pumps in Staphylococcus aureus. International Journal of Antimicrobial Agents 42 (6), pp. 513-518. ISSN 0924-8579.

Osman, Khadijo and Evangelopoulos, Dimitrios and Basavannacharya, Chandrakala and Gupta, Antima and McHugh, T.D. and Bhakta, Sanjib and Gibbons, S. (2011) An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis. International Journal of Antimicrobial Agents 39 (2), pp. 124-129. ISSN 0924-8579.

Journal of Antimicrobial Chemotherapy

Guzman, Juan D. and Pesnot, T. and Barrera, D.A. and Davies, H.M. and McMahon, E. and Evangelopoulos, Dimitrios and Mortazavi, Parisa Nakhostin and Munshi, Tulika and Maitra, Arundhati and Lamming, E.D. and Angell, R. and Gershater, M.C. and Redmond, J.M. and Needham, D. and Ward, J.M. and Cuca, L.E. and Hailes, H.C. and Bhakta, Sanjib (2015) Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase. Journal of Antimicrobial Chemotherapy 70 (6), pp. 1691-1703. ISSN 0305-7453.

Guzman, Juan D. and Wube, A. and Evangelopoulos, Dimitrios and Gupta, Antima and Hufner, A. and Basavannacharya, Chandrakala and Rahman, M.M. and Thomaschitz, C. and Bauer, R. and McHugh, T.D. and Nobeli, Irene and Prieto, J.M. and Gibbons, S. and Bucar, F. and Bhakta, Sanjib (2011) Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics. Journal of Antimicrobial Chemotherapy 66 (8), pp. 1766-1772. ISSN 0305-7453.

Guzman, Juan D. and Gupta, Antima and Evangelopoulos, Dimitrios and Basavannacharya, Chandrakala and Pabon, L.C. and Plazas, E.A. and Munoz, D.R. and Delgado, W.A. and Cuca, L.E. and Ribon, W. and Gibbons, S. and Bhakta, Sanjib (2010) Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. Journal of Antimicrobial Chemotherapy 65 (10), pp. 2101-2107. ISSN 0305-7453.

Journal of Applied Microbiology

Hochfellner, C. and Evangelopoulos, Dimitrios and Zloh, M. and Wube, A. and Guzman, J.D. and McHugh, T.D. and Kunert, O. and Bhakta, Sanjib and Bucar, F. (2015) Antagonistic effects of indoloquinazoline alkaloids on antimycobacterial activity of evocarpine. Journal of Applied Microbiology 118 (4), pp. 864-872. ISSN 1364-5072.

Journal of Ethnopharmacology

Zhao, J. and Evangelopoulos, Dimitrios and Bhakta, Sanjib and Gray, A.I. and Seidel, V. (2014) Antitubercular activity of Arctium lappa and Tussilago farfara extracts and constituents. Journal of Ethnopharmacology 155 (1), pp. 796-800. ISSN 0378-8741.

Journal of Natural Products

O’Donnell, G. and Poeschl, R. and Zimhony, O. and Gunaratnam, M. and Moreira, J.B.C. and Neidle, S. and Evangelopoulos, Dimitrios and Bhakta, Sanjib and Malkinson, J. and Boshoff, H.I. and Lenaerts, A. and Gibbons, S. (2009) Bioactive Pyridine-N-oxide Disulfides from Allium stipitatum. Journal of Natural Products 72 (3), pp. 360-365. ISSN 0163-3864.

Organic Letters

Kottakota, S.K. and Benton, M. and Evangelopoulos, Dimitrios and Guzman, Juan D. and Bhakta, Sanjib and McHugh, T.D. and Gray, M. and Groundwater, P.W. and Marrs, E.C.L. and Perry, J.D. and Harburn, J.J. (2012) Versatile routes to marine sponge metabolites through Benzylidene Rhodanines. Organic Letters 14 (24), pp. 6310-6313. ISSN 1523-7060.

PLoS One

Munshi, Tulika and Gupta, Antima and Evangelopoulos, Dimitrios and Guzman, Juan D. and Gibbons, S. and Keep, Nicholas H. and Bhakta, Sanjib (2013) Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis. PLoS One 8 (3), e60143. ISSN 1932-6203.

Phytotherapy Research

Guzman, Juan D. and Evangelopoulos, Dimitrios and Gupta, Antima and Prieto, J.M. and Gibbons, S. and Bhakta, Sanjib (2013) Antimycobacterials from Lovage Root (Ligusticum officinale Koch). Phytotherapy Research 27 (7), pp. 993-998. ISSN 0951-418X.

The Journal of Antibiotics

Bhakta, Sanjib and Guzman, Juan David and Evangelopoulos, Dimitrios and Munshi, Tulika and Mcmahon, Eleanor (2016) DNA sequence-selective C8-linked pyrrolobenzodiazepine(PBD)-heterocyclic polyamide conjugates show anti-tubercular specific activities. The Journal of Antibiotics 69 , pp. 843-849. ISSN 0021-8820.

Brucoli, F. and Guzman, Juan David and Basher, M.A. and Evangelopoulos, Dimitrios and Mcmahon, Eleanor and Munshi, Tulika and McHugh, T.D. and Fox, K.R. and Bhakta, Sanjib (2016) DNA sequence-selective C8-linked pyrrolobenzodiazepine–heterocyclic polyamide conjugates show anti-tubercular-specific activities. The Journal of Antibiotics 69 , pp. 843-849. ISSN 0021-8820.

Tuberculosis

Evangelopoulos, Dimitrios and Gupta, Antima and Lack, N. and Maitra, Arundhati and ten Bokum, A.M.C. and Kendall, Sharon L. and Sim, E. and Bhakta, Sanjib (2014) Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis. Tuberculosis 94 (6), pp. 664-671. ISSN 1472-9792.