Browse by Research Centre

A

Alber, F. and Forster, F. and Korkin, D. and Topf, Maya and Sali, A. (2008) Integrating diverse data for structure determination of macromolecular assemblies. Annual Review of Biochemistry 77 , pp. 443-477. ISSN 0066-4154.

Allen, William J. and Rothwell, P.J. and Waksman, Gabriel (2008) An intramolecular FRET system monitors fingers subdomain opening in Klentaq1. Protein Science 17 (3), pp. 401-408. ISSN 0961-8368.

B

Backert, S. and Fronzes, Remi and Waksman, Gabriel (2008) VirB2 and VirB5 proteins: specialized adhesins in bacterial type-IV secretion systems? Trends in Microbiology 16 (9), pp. 409-413. ISSN 0966-842X.

Bagneris, Claire and Ageichik, A.V. and Cronin, Nora and Wallace, Bonnie A. and Collins, M. and Boshoff, C. and Waksman, Gabriel and Barrett, Tracey E. (2008) Crystal structure of a vFlip-IKK gamma complex: Insights into viral activation of the IKK signalosome. Molecular Cell 30 (5), pp. 620-631. ISSN 1097-2765.

Bagneris, Claire and Ageichik, A.V. and Cronin, Nora and Wallace, Bonnie A. and Collins, M. and Boshoff, C. and Waksman, Gabriel and Barrett, Tracey E. (2008) Crystal structure of a vFlip-IKKγ Complex: insights into viral activation of the IKK Signalosome. Molecular Cell 30 (5), pp. 620-631. ISSN 1097-2765.

Baldwin, A.J. and Anthony-Cahill, S.J. and Knowles, T.P.J. and Lippens, G. and Christodoulou, John and Barker, P.D. and Dobson, C.M. (2008) Measurement of amyloid fibril length distributions by inclusion of rotational motion in solution NMR diffusion measurements. Angewandte Chemie - International Edition 47 (18), pp. 3385-3387. ISSN 1433-7851.

Bashton, M. and Nobeli, Irene and Thornton, Janet M. (2008) Procognate: a cognate ligand domain mapping for enzymes. Nucleic Acids Research 36 , D618-D622. ISSN 0305-1048.

Booth, C.R. and Meyer, A.S. and Cong, Y. and Topf, Maya and Sali, A. and Ludtke, Steven J. and Chiu, W. and Frydman, J. (2008) Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT. Nature Structural and Molecular Biology 15 (7), pp. 746-753. ISSN 1545-9993.

Bulheller, B.M. and Miles, Andrew J. and Wallace, Bonnie A. and Hirst, J.D. (2008) Charge-transfer transitions in the vacuum-ultraviolet of protein circular dichroism spectra. Journal of Physical Chemistry B 112 (6), pp. 1866-1874. ISSN 1520-6106.

C

Chan, P.H. and Pardon, E. and Menzer, L. and de Genst, E. and Kumita, J.R. and Christodoulou, John and Saerens, D. and Brans, A. and Bouillenne, F. and Archer, D.B. and Robinson, C.V. and Muyldermans, S. and Matagne, A. and Redfield, C. and Wyns, L. and Dobson, C.M. and Demoulin, M. (2008) Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils. Biochemistry 47 (42), pp. 11041-11054. ISSN 0006-2960.

Chandramouli, P. and Topf, Maya and Menetret, J.F. and Eswar, N. and Cannone, J.J. and Gutell, R.R. and Sali, A. and Akey, C.W. (2008) Structure of the mammalian 80S ribosome at 87 angstrom resolution. Structure 16 (4), pp. 535-548. ISSN 0969-2126.

Ciccia, A. and McDonald, Neil Q. and West, S.C. (2008) Structural and functional relationships of the XPF/MUS81 family of proteins. Annual Review of Biochemistry 77 , pp. 259-287. ISSN 0066-4154.

Ciferri, C. and Pasqualato, S. and Screpanti, E. and Varetti, G. and Santaguida, S. and dos Reis, G. and Maiolica, A. and Polka, J. and de Luca, J.G. and de Wulf, P. and Salek, M. and Rappsilber, J. and Moores, Carolyn A. and Salmon, E.D. and Musacchio, A. (2008) Implications for Kinetochore-Microtubule attachment from the structure of an engineered Ndc80 complex. Cell 133 (3), pp. 427-439. ISSN 0092-8674.

Clare, Daniel K. and Stagg, S. and Quispe, J. and Farr, G.W. and Horwich, A.L. and Saibil, Helen R. (2008) Multiple states of a Nucleotide-Bound Group 2 Chaperonin. Structure 16 (4), pp. 528-534. ISSN 0969-2126.

Clegg, A.B. and Shepherd, Adrian J. (2008) Text Mining. Methods in Molecular Biology 453 (4), pp. 471-491. ISSN 1064-3745.

Clokie, M.R.J. and Thalassinos, Konstantinos and Boulanger, P. and Slade, S.E. and Stoilova-McPhie, S. and Cane, M. and Scrivens, J.H. and Mann, N.H. (2008) A proteomic approach to the identification of the major virion structural proteins of the marine cyanomyovirus S-PM2. Microbiology 154 (6), pp. 1775-1782. ISSN 1350-0872.

Cong, Y. and Topf, Maya and Sali, A. and Matsudaira, P. and Dougherty, M. and Chiu, W. and Schmid, M.F. (2008) Crystallographic conformers of Actin in a biologically active bundle of filaments. Journal of Molecular Biology 375 (2), pp. 331-336. ISSN 0022-2836.

Connell, S.R. and Topf, Maya and Qin, Y. and Wilson, D.N. and Mielke, T. and Fucini, P. and Nierhaus, K.H. and Spahn, C.M.T. (2008) A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 , pp. 910-915. ISSN 1545-9985.

Cowieson, N.P. and Miles, Andrew J. and Robin, G. and Forwood, J.K. and Kobe, B. and Martin, J.L. and Wallace, Bonnie A. (2008) Evaluating protein : protein complex formation using synchrotron radiation circular dichroism spectroscopy. Proteins-Structure, Function and Bioinformatics 70 (2), pp. 1142-1146. ISSN 0887-3585.

D

Davies, M.N. and Lamikanra, A. and Sansom, Clare E. and Flower, D.R. and Moss, David S. and Travers, P.J. (2008) Identification of the HLA-DM/HLA-DR interface. Molecular Immunology 45 (4), pp. 1063-1070. ISSN 0161-5890.

Davies, M.N. and Secker, A. and Halling-Brown, Mark D. and Moss, David S. and Freitas, A.A. and Timmis, J. and Clark, E. and Flower, D.R. (2008) GPCRTree: online hierarchical classification of GPCR function. BMC Research Notes 1 , p. 67. ISSN 1756-0500.

Davies, T.G.E. and O’Reilly, Andrias O. and Field, L.M. and Wallace, Bonnie A. and Williamson, M.S. (2008) Knockdown resistance to DDT and pyrethroids: from target-site mutations to molecular modelling. Pest Management Science 64 (11), pp. 1126-1130. ISSN 1526-498X.

Depril, D. and van Mechelen, I. and Mirkin, Boris (2008) Algorithms for additive clustering of rectangular data tables. Computational Statistics & Data Analysis 52 (11), pp. 4923-4938. ISSN 0167-9473.

de Fabritiis, G. and Geroult, S. and Coveney, P.V. and Waksman, Gabriel (2008) Insights from the energetics binding at the domain-ligand of the Src SH2 domain of water interface. Proteins-Structure, Function and Bioinformatics 72 (4), p. 1290. ISSN 0887-3585.

E

Elad, Nadav and Clare, Daniel K. and Saibil, Helen R. and Orlova, Elena (2008) Detection and separation of heterogeneity in molecular complexes by statistical analysis of their two-dimensional projections. Journal of Structural Biology 162 (1), pp. 108-120. ISSN 1047-8477.

Erlandson, K.J. and Miller, S.B.M. and Nam, Y. and Osborne, Andrew R. and Zimmer, J. and Rapoport, T.A. (2008) A role for the two-helix finger of the SecA ATPase in protein translocation. Nature 455 (7215), pp. 984-987. ISSN 0028-0836.

Erlandson, K.J. and Or, E. and Osborne, Andrew R. and Rapoport, T.A. (2008) Analysis of Polypeptide movement in the SecY channel during SecA-mediated protein translocation. Journal of Biological Chemistry 283 (23), pp. 15709-15715. ISSN 0021-9258.

Evans, P. and Slingsby, Christine and Wallace, Bonnie A. (2008) Association of partially folded lens beta B2-crystallins with the alpha-crystallin molecular chaperone. Biochemical Journal 409 , pp. 691-699. ISSN 0264-6021.

F

Favia, A.D. and Nobeli, Irene and Glaser, F. and Thornton, Janet M. (2008) Molecular docking for substrate identification: the short-chain dehydrogenases/reductases. Journal of Molecular Biology 375 (3), pp. 855-874. ISSN 0022-2836.

Fronzes, Remi and Remaut, Han and Waksman, Gabriel (2008) Architectures and biogenesis of non-flagellar protein appendages in gram-negative bacteria. Embo Journal 27 (17), pp. 2271-2280. ISSN 0261-4189.

Fulton, D.C. and Stettler, M. and Mettler, T. and Vaughan, Cara K. and Li, J. and Francisco, P. and Gil, D. and Reinhold, H. and Eicke, S. and Messerli, G. and Dorken, G. and Halliday, K. and Smith, Adrian M.L. and Smith, S.M. and Zeeman, S.C. (2008) beta-AMYLASE4, a noncatalytic protein required for starch breakdown, acts upstream of three active beta-amylases in arabidopsis chloroplasts. Plant Cell 20 (4), pp. 1040-1058. ISSN 1040-4651.

G

Galán, J.E. and Campellone, K.G. and Cheng, H.-C. and Robbins, D. and Siripala, A.D. and McGhie, E.J. and Hayward, Richard D. and Welch, M.D. and Rosen, M.K. and Koronakis, V. and Leong, J.M. (2008) Repetitive N-WASP–binding elements of the Enterohemorrhagic Escherichia coli Effector EspFU Synergistically Activate Actin Assembly. PLoS Pathogens 4 (10), e1000191. ISSN 1553-7374.

Garg, R. and Riento, K. and Keep, Nicholas H. and Morris, J.D.H. and Ridley, A.J. (2008) N-terminus-mediated dimerization of ROCK-1 is required for RhoE binding and actin reorganization. Biochemical Journal 411 , pp. 407-414. ISSN 0264-6021.

Gooptu, Bibek and Lomas, D.A. (2008) Polymers and inflammation: disease mechanisms of the serpinopathies. The Journal of Experimental Medicine 205 (7), pp. 1529-1534. ISSN 0022-1007.

Gsponer, J. and Christodoulou, John and Cavalli, A. and Bui, J.M. and Richter, B. and Dobson, C.M. and Vendruscolo, M. (2008) A coupled equilibrium shift mechanism in Calmodulin-Mediated signal transduction. Structure 16 (5), pp. 736-746. ISSN 0969-2126.

H

Halling-Brown, Mark D. and Moss, David S. and Shepherd, Adrian J. (2008) Towards a lightweight generic computational grid framework for biological research. BMC Bioninformatics 9 , ISSN 1471-2105.

Halling-Brown, Mark D. and Sansom, Clare E. and Davies, M.N. and Titball, R.W. and Moss, David S. (2008) Are bacterial vaccine antigens T-cell epitope depleted? Trends in Immunology 29 (8), pp. 374-379. ISSN 1471-4906.

Halling-Brown, Mark D. and Shepherd, Adrian J. (2008) Constructing computational pipelines. Methods in Molecular Biology 453 (4), pp. 451-470. ISSN 1064-3745.

Hardman, S.J.O. and Botchway, S.W. and Thompson, Katherine C. (2008) Evidence for a nonbase stacking effect for the environment-sensitive fluorescent base Pyrrolocytosine-comparison with 2-Aminopurine. Photochemistry & Photobiology 84 (6), pp. 1473-1479. ISSN 0031-8655.

Harvey, R.J. and Topf, Maya and Harvey, K. and Rees, M.I. (2008) The genetics of hyperekplexia: more than startle! Trends in Genetics 24 (9), pp. 439-447. ISSN 0168-9525.

Hawkins, T.A. and Haramis, A.P. and Etard, C. and Prodromou, C. and Vaughan, Cara K. and Ashworth, R. and Ray, S. and Behra, M. and Holder, N. and Talbot, W.S. and Pearl, L.H. and Strahlem, U. and Wilson, S.W. (2008) The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis. Development 135 , pp. 1147-1156. ISSN 0950-1991.

Hilton, G.R. and Jackson, A.T. and Thalassinos, Konstantinos and Scrivens, J.H. (2008) Structural analysis of synthetic polymer mixtures using ion mobility and tandem mass spectrometry. Analytical Chemistry 80 (24), pp. 9720-9725. ISSN 0003-2700.

Huang, J.R. and Hsu, S.T.D. and Christodoulou, John and Jackson, S.E. (2008) The extremely slow-exchanging core and acid-denatured state of green fluorescent protein. Hfsp Journal 2 (6), pp. 378-387. ISSN 1955-2068.

I

Iqbal, A. and Wang, L. and Thompson, Katherine C. and Lilley, D.M.J. and Norman, D.G. (2008) The structure of cyanine 5 terminally attached to double-stranded DNA: implications for FRET studies. Biochemistry 40 (30), pp. 7857-7862. ISSN 0006-2960.

Isberg, R.R. and Hayward, Richard D. and Cain, R.J. and Koronakis, V. (2008) Deciphering interplay between Salmonella invasion effectors. PLoS Pathogens 4 (4), e1000037. ISSN 1553-7374.

J

Jackson, A.T. and Slade, S.E. and Thalassinos, Konstantinos and Scrivens, J.H. (2008) End-group characterisation of poly(propylene glycol)s by means of electrospray ionisation–tandem mass spectrometry (ESI-MS/MS). Analytical and Bioanalytical Chemistry 392 (4), pp. 643-650. ISSN 1618-2642.

K

King, M.D. and Thompson, Katherine C. and Ward, A.D. and Pfrang, C. and Hughes, Brian R. (2008) Oxidation of biogenic and water-soluble compounds in aqueous and organic aerosol droplets by ozone: a kinetic and product analysis approach using laser Raman tweezers. Faraday Discussions 137 , pp. 173-192. ISSN 1359-6640.

Kirk, R. and Laman, H. and Knowles, P.P. and Murray-Rust, J. and Lomonosov, M. and Meziane, E.K. and McDonald, Neil Q. (2008) Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor. Journal of Biological Chemistry 283 (32), pp. 22325-22335. ISSN 0021-9258.

Krojer, T. and Sawa, J. and Schafer, Eva and Saibil, Helen R. and Ehrmann, M. and Clausen, T. (2008) Structural basis for the regulated protease and chaperone function of DegP. Nature (453), pp. 885-890. ISSN 0028-0836.

L

Lampert, A. and O’Reilly, Andrias O. and Dib-Hajj, S.D. and Tyrrell, L. and Wallace, Bonnie A. and Waxman, S.G. (2008) A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Na(v)17 channel is disrupted by the erythromelalgia-associated F1449V mutation. Journal of Biological Chemistry 283 , pp. 24118-24127. ISSN 0021-9258.

Lukoyanova, Natalya and Saibil, Helen R. (2008) Friend or foe: the same fold for attack and defense. Trends in Immunology 29 (2), pp. 51-53. ISSN 1471-4906.

M

Milanesi, Lilia and Tomas, Salvador and Hunter, C.A. and Weinstein, J.A. and Edge, R. and Navaratnam, S. and Waltho, J.P. and Best, J. (2008) A pulse-radiolysis approach to fast reductive cleavage of a disulfide bond to uncage enzyme activity. Free Radical Biology and Medicine 45 (9), pp. 1271-1278. ISSN 0891-5849.

Miles, Andrew J. and Drechsler, A. and Kristan, K. and Anderluh, G. and Norton, R.S. and Wallace, Bonnie A. and Separovic, F. (2008) The effects of lipids on the structure of the eukaryotic cytolysin equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study. Biochimica et Biophysica Acta (BBA) - Biomembranes 1778 (10), pp. 2091-2096. ISSN 0006-3002.

Miles, Andrew J. and Hoffmann, S.V. and Tao, Y. and Janes, R.W. and Wallace, Bonnie A. (2008) Synchrotron radiation circular dichroism (SRCD) spectroscopy: new beamlines and new applications in biology. Spectroscopy 21 (5-6), pp. 245-255. ISSN 0712-4813.

Miles, Andrew J. and Janes, R.W. and Brown, A. and Clarke, D.T. and Sutherland, J.C. and Tao, Y. and Wallace, Bonnie A. and Hoffmann, S.V. (2008) Light flux density threshold at which protein denaturation is induced by synchrotron radiation circular dichroism beamlines. Journal of Synchrotron Radiation 15 , pp. 420-422. ISSN 0909-0495.

Miller, P.S. and Topf, Maya and Smart, T.G. (2008) Mapping a molecular link between allosteric inhibition and activation of the glycine receptor. Nature Structural & Molecular Biology 15 , pp. 1084-1093. ISSN 1545-9985.

Millson, S.H. and Vaughan, Cara K. and Zhai, C. and Ali, M.M.U. and Panaretou, B. and Piper, P.W. and Pearl, L.H. and Prodromou, C. (2008) Chaperone ligand-discrimination by the TPR-domain protein Tah1. Biochemical Journal 413 , pp. 261-268. ISSN 0264-6021.

Mirkin, Boris and Gutman, P.O. (2008) Robust output-feedback model reference adaptive control of SISO plants with multiple uncertain, time-varying state delays. IEEE Transactions on Automatic Control 53 (10), pp. 2414-2419. ISSN 0018-9286.

Mirkin, Boris and Mirkin, E.L. and Gutman, P.O. (2008) Model reference adaptive control of nonlinear plant with dead time. In: UNSPECIFIED (ed.) IEEE Conference on Decision and Control. New York, USA: Institute of Electrical and Electronics Engineers, pp. 1920-1924. ISBN 9781424431236.

Mirkin, Boris and Nascimento, S. and Pereira, L.M. (2008) Representing a computer science research organization on the ACM computing classification system. Supplementary Proceedings of the 16th International Conference on Conceptual Structures 354 , pp. 57-65. ISSN 1613-0073.

Moores, Carolyn A. (2008) Studying microtubules by electron microscopy. Introduction to Electron Microscopy for Biologists 88 , pp. 299-317. ISSN 0091-679X.

Moores, Carolyn A. and Milligan, R.A. (2008) Visualisation of a kinesin-13 motor on microtubule end mimics. Journal of Molecular Biology 377 (3), pp. 647-654. ISSN 0022-2836.

Mouilleron, S. and Guettler, S. and Langer, C.A. and Treisman, R. and McDonald, Neil Q. (2008) Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL. The EMBO Journal 27 (23), pp. 3198-3208. ISSN 1460-2075.

N

Nurani, G. and Radford, M. and O’Reilly, Andrias O. and Cronin, Nora and Haque, S. and Wallace, Bonnie A. (2008) Tetrameric bacterial sodium channels: characterization of structure, stability, and drug binding. Biochemistry 47 (31), pp. 8114-8121. ISSN 0006-2960.

O

Olsson, T.S.G. and Williams, Mark A. and Pitt, W.R. and Ladbury, J.E. (2008) The thermodynamics of protein–ligand interaction and solvation: insights for ligand design. Journal of Molecular Biology 384 (4), pp. 1002-1017. ISSN 0022-2836.

O’Reilly, Andrias O. and Nurani, G. and Powl, Andrew M. and Charalambous, Kalypso and Wallace, Bonnie A. (2008) G219S mutagenesis as a means of stabilizing conformational flexibility in the bacterial sodium channel NaChBac. Molecular Membrane Biology 25 (8), pp. 670-676. ISSN 0968-7688.

P

Pappalardo, F. and Zhang, P. and Halling-Brown, Mark D. and Basford, K.E. and Scalia, A. and Shepherd, Adrian J. and Moss, David S. and Motta, S. and Brusic, V. (2008) Computational simulations of the immune system for personalized medicine: state of the art and challenges. Current Pharmacogenomics and Personalized Medicine 6 (4), pp. 260-271. ISSN 1875-6921.

Patel, P. and Harris, R. and Geddes, Stella M. and Strehle, E.M. and Watson, J.D. and Bashir, R. and Bushby, K. and Driscoll, P.C. and Keep, Nicholas H. (2008) Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b. Journal of Molecular Biology 379 (5), pp. 981-990. ISSN 0022-2836.

R

Remaut, Han and Tang, C. and Henderson, N.S. and Pinkner, J.S. and Wang, T. and Hultgren, S.J. and Thanassi, D.G. and Waksman, Gabriel and Li, H.L. (2008) Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell 133 (4), pp. 640-652. ISSN 0092-8674.

Rivers, R.C. and Kumita, J.R. and Tartaglia, G.G. and Dedmon, M.M. and Pawar, A. and Vendruscolo, M. and Dobson, C.M. and Christodoulou, John (2008) Molecular determinants of the aggregation behavior of alpha- and beta-synuclein. Protein Science 17 (5), pp. 887-898. ISSN 0961-8368.

Roces, L. and Knowles, P.P. and Fox, G. and Juanhuix, J. and Scaplehorn, N. and Way, M. and McDonald, Neil Q. (2008) Crystallization and preliminary X-ray diffraction analysis of vaccinia virus H1L phosphatase. Acta Crystallographica Section F F64 (3), pp. 190-192. ISSN 1744-3091.

Roodveldt, C. and Bertoncini, C.W. and Andersson, A. and van der Goot, A.T. and Hsu, S.T.D. and Fernandez Montesinos, R. and de Jong, J. and van Ham, T.J. and Nollen, E.A. and Pozo, D. and Christodoulou, John and Dobson, C.M. (2008) Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip. Embo Journal 28 (23), pp. 3758-3770. ISSN 0261-4189.

Roodveldt, C. and Christodoulou, John and Dobson, C.M. (2008) Immunological features of alpha-synuclein in Parkinson's disease. Journal of Cellular and Molecular Medicine 12 (5B), pp. 1820-1829. ISSN 1582-1838.

Rose, R.J. and Verger, Denis and Daviter, Tina and Remaut, Han and Paci, E. and Waksman, Gabriel and Ashcroft, A.E. and Radford, S.E. (2008) Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America 105 (35), pp. 12873-12878. ISSN 0027-8424.

Rose, R.J. and Welsh, T.S. and Waksman, Gabriel and Ashcroft, A.E. and Radford, S.E. and Paci, E. (2008) Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics. Journal of Molecular Biology 375 (4), pp. 908-919. ISSN 0022-2836.

S

Saibil, Helen R. (2008) Chaperone machines in action. Current Opinion in Structural Biology 18 (1), pp. 35-42. ISSN 0959-440X.

Salih, O. and Remaut, Han and Waksman, Gabriel and Orlova, Elena (2008) Structural analysis of the Saf pilus by electron microscopy and image processing. Journal of Molecular Biology 379 (1), pp. 174-187. ISSN 0022-2836.

Scarff, C.A. and Thalassinos, Konstantinos and Hilton, G.R. and Scrivens, J.H. (2008) Travelling wave ion mobility mass spectrometry studies of protein structure: biological significance and comparison with X-ray crystallography and nuclear magnetic resonance spectroscopy measurements. Rapid Communications in Mass Spectrometry 22 (20), pp. 3297-3304. ISSN 0951-4198.

Serysheva, I.I. and Baker, M.L. and Cong, Y. and Topf, Maya and Eramian, D. and Sali, A. and Hamilton, S.L. and Chiu, W. (2008) Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proceedings of the National Academy of Sciences of the United States of America 105 (28), pp. 9610-9615. ISSN 0027-8424.

Shepherd, Adrian J. and Clegg, A.B. (2008) Syntactic pattern matching with GraphSpider and MPL. In: Proceedings of the Third Symposium on Semantic Mining in Biomedicine, September 1-3 2008, Turku, Finland.

Shepherd, Adrian J. and Kabiljo, R. (2008) Protein name tagging in the immunological domain. In: Proceedings of the Third Symposium on Semantic Mining in Biomedicine, September 1-3 2008, Turku, Finland.

Siepen, J.A. and Belhajjame, K. and Selley, J.N. and Embury, S.M. and Paton, N.W. and Goble, C.A. and Oliver, S.G. and Stevens, R. and Zamboulis, Lucas and Martin, Nigel and Poulovassilis, Alexandra and Jones, P. and Côté, R. and Hermjakob, H. and Pentony, M.M. and Jones, D.T. and Orengo, C.A. and Hubbard, S.J. (2008) ISPIDER Central: an integrated database web-server for proteomics. Nucleic Acids Research 36 (2), W485-W490. ISSN 0305-1048.

Sim, E. and Sandy, J. and Evangelopoulos, Dimitrios and Fullam, E. and Bhakta, Sanjib and Westwood, I.M. and Krylova, A. and Lack, N. and Noble, M. (2008) Arylamine N-acetyltransferases in mycobacteria. Current Drug Metabolism 9 (6), pp. 510-519. ISSN 1389-2002.

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Taylor, J.D. and Ababou, A. and Fawaz, R.R. and Hobbs, C.J. and Williams, Mark A. and Ladbury, J.E. (2008) Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: implications for drug design. Proteins: Structure, Function, and Bioinformatics 73 (4), pp. 929-940. ISSN 0887-3585.

Thornton, Janet M. and Favia, A.D. and Nobeli, Irene and Furnham, N. (2008) The evolution of specificity in large protein families. In: 33rd FEBS Congress & 11th IUBMB Conference: Biochemistry of Cell Regulation, June 28-July 3 2008, Athens, Greece.

Todman, S.J. and Halling-Brown, Mark D. and Davies, M.N. and Flower, D.R. and Kayikci, M. and Moss, David S. (2008) Toward the atomistic simulation of T cell epitopes automated construction of MHC: peptide structures for free energy calculations. Journal of Molecular Graphics and Modelling 26 (6), pp. 957-961. ISSN 1093-3263.

Topf, Maya and Lasker, K. and Webb, B. and Wolfson, H.J. and Chiu, W. and Sali, A. (2008) Protein structure fitting and refinement guided by cryo-EM density. Structure 16 (2), pp. 295-307. ISSN 0969-2126.

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Vaughan, Cara K. and Mollapour, M. and Smith, J.R. and Truman, A.W. and Hu, B. and Good, V.M. and Panaretou, B. and Neckers, L. and Clarke, P.A. and Workman, P. and Piper, P.W. and Prodromou, C. and Pearl, L.H. (2008) Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37. Molecular Cell 31 (6), pp. 886-895. ISSN 1097-2765.

Verger, Denis and Rose, R.J. and Paci, E. and Costakes, G. and Daviter, Tina and Hultgren, S.J. and Remaut, Han and Ashcroft, A.E. and Radford, S.E. and Waksman, Gabriel (2008) Structural determinants of polymerization reactivity of the P pilus Adaptor Subunit PapF. Structure 16 (11), pp. 1724-1731. ISSN 0969-2126.

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Waksman, Gabriel and Meng, G.Y. and St. Geme, J.W. (2008) Repetitive architecture of the Haemophilus influenzae hia trimeric autotransporter. Journal of Molecular Biology 384 (4), pp. 824-836. ISSN 0022-2836.

Whitmore, Lee and Wallace, Bonnie A. (2008) Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases. Biopolymers 89 (5), pp. 392-400. ISSN 0006-3525.

Y

Yeats, C. and Lees, J. and Reid, A. and Kellam, P. and Martin, Nigel and Liu, X. and Orengo, C.A. (2008) Gene3D: comprehensive structural and functional annotation of genomes. Nucleic Acids Research 36 (S1), D414-D418. ISSN 0305-1048.