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1 October 2006
Moores, Carolyn A. and Milligan, R.A. (2006) Lucky 13-microtubule depolymerisation by kinesin-13 motors. Journal of Cell Science 119 (Pt 19), pp. 3905-13. ISSN 0021-9533.
2008
Moores, Carolyn A. (2008) Studying microtubules by electron microscopy. Introduction to Electron Microscopy for Biologists 88 , pp. 299-317. ISSN 0091-679X.
March 2008
Moores, Carolyn A. and Milligan, R.A. (2008) Visualisation of a kinesin-13 motor on microtubule end mimics. Journal of Molecular Biology 377 (3), pp. 647-654. ISSN 0022-2836.
May 2008
Ciferri, C. and Pasqualato, S. and Screpanti, E. and Varetti, G. and Santaguida, S. and dos Reis, G. and Maiolica, A. and Polka, J. and de Luca, J.G. and de Wulf, P. and Salek, M. and Rappsilber, J. and Moores, Carolyn A. and Salmon, E.D. and Musacchio, A. (2008) Implications for Kinetochore-Microtubule attachment from the structure of an engineered Ndc80 complex. Cell 133 (3), pp. 427-439. ISSN 0092-8674.
February 2009
Bodey, Andrew J. and Kikkawa, M. and Moores, Carolyn A. (2009) The ATP state of a mitotic Kinesin-5 bound to microtubules. Biophysical Journal 96 (3(S1)), 215a-215a. ISSN 0006-3495.
April 2009
Mulder, A.M. and Glavis-Bloom, A. and Moores, Carolyn A. and Wagenbach, M. and Carragher, B. and Wordeman, L. and Milligan, R.A. (2009) A new model for binding of kinesin 13 to curved microtubule protofilaments. Journal of Cell Biology 185 (1), pp. 51-57. ISSN 0021-9525.
May 2009
Bodey, Andrew J. and Kikkawa, M. and Moores, Carolyn A. (2009) 9-Angström structure of a microtubule-bound mitotic motor. Journal of Molecular Biology 388 (2), pp. 218-224. ISSN 0022-2836.
2010
Peters, Carsten and Brejc, K. and Belmont, L. and Bodey, Andrew J. and Lee, Y. and Yu, M. and Guo, J. and Sakowicz, R. and Hartman, J. and Moores, Carolyn A. (2010) Insight into the molecular mechanism of the multitasking kinesin-8 motor. The EMBO Journal 29 (20), pp. 3437-3447. ISSN 0261-4189.
January 2010
Peters, Carsten and Brejc, K. and Belmont, L. and Bodey, Andrew J. and Lee, Y. and Yu, M. and Ramchandani, S. and Guo, J. and Lichtsteiner, S. and Wood, K. and Sakowicz, R. and Hartman, J. and Moores, Carolyn A. (2010) The molecular mechanism of the multi-tasking Kinesin-8 motor. Biophysical Journal 98 (3(S1)), 166a-166a. ISSN 0006-3495.
March 2010
Fourniol, Franck J. and Moores, Carolyn A. (2010) Kinesin motor activation: microtubules pull the switches. Proceedings of the National Academy of Sciences of the United States of America 107 (9), pp. 3949-3950. ISSN 0027-8424.
April 2010
Moores, Carolyn A. (2010) Kinesin-5 mitotic motors: is loop5 the on/off switch? Cell Cycle 9 (7), pp. 1286-1290. ISSN 1551-4005.
1 November 2010
Fourniol, Franck J. and Sindelar, C.V. and Amigues, B. and Clare, Daniel K. and Thomas, G. and Perderiset, M. and Francis, F. and Houdusse, A. and Moores, Carolyn A. (2010) Template-free 13-protofilament microtubule–MAP assembly visualized at 8 A resolution. The Journal of Cell Biology 191 (3), pp. 463-470. ISSN 0021-9525.
2011
Behnke-Parks, W.M. and Vendome, J. and Honig, B. and Maliga, Z. and Moores, Carolyn A. and Rosenfeld, S.S. (2011) Loop L5 acts as a conformational latch in the Mitotic Kinesin Eg5. Journal of Biological Chemistry 286 (7), pp. 5242-5253. ISSN 0021-9258.
Fourniol, Franck J. and Moores, Carolyn A. (2011) Snapshots of kinesin motors on microtubule tracks. Methods in Molecular Biology 778 , pp. 57-70. ISSN 1064-3745.
February 2011
Moores, Carolyn A. and Peters, Carsten and Brejc, K. and Belmont, L. and Bodey, Andrew J. and Lee, Y. and Yu, M. and Guo, J. and Sakowicz, R. and Hartman, J. (2011) Small loops make a big difference: insight into the molecular mechanism of the multi-tasking Kinesin-8 Motor. Biophysical Journal 100 (3), 3a-3a. ISSN 0006-3495.
13 April 2012
Maurer, S.P. and Fourniol, Franck J. and Bohner, G. and Moores, Carolyn A. and Surrey, T. (2012) EBs recognize a nucleotide-dependent structural cap at growing microtubule ends. Cell 149 (2), pp. 371-382. ISSN 0092-8674.
14 September 2012
Liu, J.S. and Schubert, C.R. and Fu, X. and Fourniol, Franck J. and Jaiswal, J.K. and Houdusse, A. and Stultz, C.M. and Moores, Carolyn A. and Walsh, C.A. (2012) Molecular basis for specific regulation of neuronal Kinesin-3 motors by Doublecortin family proteins. Molecular Cell 47 (5), pp. 707-721. ISSN 1097-2765.
10 October 2012
Moores, Carolyn A. (2012) Dynein: a force (generation mechanism) to be reckoned with. Structure 20 (10), pp. 1611-1612. ISSN 0969-2126.
28 December 2012
Goulet, Adeline and Behnke-Parks, W.M. and Sindelar, C.V. and Major, J. and Rosenfeld, S.S. and Moores, Carolyn A. (2012) The structural basis of force generation by the Mitotic motor Kinesin-5. Journal of Biological Chemistry 287 , pp. 44654-44666. ISSN 0021-9258.
2013
Muretta, J.M. and Behnke-Parks, W.M. and Major, J. and Petersen, K.J. and Goulet, A. and Moores, Carolyn A. and Thomas, D.D. and Rosenfeld, S.S. (2013) Loop L5 assumes three distinct orientations during the ATpase cycle of the mitotic kinesin eg5: a transient and time-resolved flourescence study. Journal of Biological Chemistry 288 (48), pp. 34839-34849. ISSN 0021-9258.
Bahi-Buisson, N. and Souville, I. and Fourniol, Franck J. and Toussaint, A. and Moores, Carolyn A. and Houdusse, A. and Yves Lemaitre, J. and Poirier, K. and Khalaf-Nazzal, R. and Hully, M. and Louis Leger, P. and Elie, C. and Boddaert, N. and Beldjord, C. and Chelly, J. and Francis, F. (2013) New insights into genotype-phenotype correlations for the doublecortin-related lissencephaly spectrum. Brain 136 (1), pp. 223-244. ISSN 1460-2156.
Goulet, Adeline and Moores, Carolyn A. (2013) New insights into the mechanism of force generation by Kinesin-5 molecular motors. In: Jeon, K.W. (ed.) International Review of Cell and Molecular Biology. New York, U.S.: Elsevier, pp. 419-466. ISBN 9780124076969.
Fourniol, Franck J. and Perderiset, M. and Houdusse, A. and Moores, Carolyn A. (2013) Structural studies of the Doublecortin family of MAPs. In: Correia, J.J. and Wilson, L. (eds.) Microtubules, In Vitro (2nd Edition). Methods In Cell Biology 115. New York, U.S.: Elsevier, pp. 27-48. ISBN 9780124077577.
October 2013
Atherton, Joseph and Houdusse, A. and Moores, Carolyn A. (2013) MAPping out distribution routes for kinesin couriers. Biology of the Cell 105 (10), pp. 465-487. ISSN 0248-4900.
29 November 2013
Randall, T.S. and Moores, Carolyn A. and Stephenson, F.A. (2013) Delineation of the TRAK binding regions of the kinesin-1 motor proteins. FEBS Letters 587 (23), pp. 3763-3769. ISSN 1873-3468.
4 February 2014
Goulet, Adeline and Major, J. and Jung, Y. and Grossmann, S.P. and Rosenfeld, S.S. and Moores, Carolyn A. (2014) Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family. Proceedings of the National Academy of Sciences of the United States of America 111 (5), pp. 1837-1842. ISSN 0027-8424.
September 2014
Bullen, A. and Taylor, R.R. and Kachar, B. and Moores, Carolyn A. and Fleck, R.A. and Forge, A. (2014) Inner ear tissue preservation by rapid freezing: improving fixation by high-pressure freezing and hybrid methods. Hearing Research 315 , pp. 49-60. ISSN 0378-5955.
10 September 2014
Atherton, Joseph and Farabella, Irene and Yu, I-M. and Rosenfeld, S.S. and Houdusse, A. and Topf, Maya and Moores, Carolyn A. (2014) Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins. eLife 3 , ISSN 2050-084X.
4 June 2015
Bullen, A. and West, T. and Moores, Carolyn A. and Ashmore, J. and Fleck, R.A. and MacLellan-Gibson, K. and Forge, A. (2015) Association of intracellular and synaptic organization in cochlear inner hair cells revealed by 3D electron microscopy. Journal of Cell Science 128 , pp. 2529-2540. ISSN 0021-9533.
20 October 2015
Scarabelli, G. and Soppina, V. and Yao, X. and Atherton, J. and Moores, Carolyn A. and Verhey, K.J. and Grant, B.J. (2015) Mapping the processivity determinants of the kinesin-3 motor domain. Biophysical Journal 109 (8), pp. 1537-1540. ISSN 0006-3495.
17 June 2016
Vemu, A. and Atherton, Joe and Spector, J.O. and Szyk, A. and Moores, Carolyn A. and Roll-Mecak, A. (2016) Structure and dynamics of single-isoform recombinant Neuronal Human Tubulin. Journal of Biological Chemistry 291 (25), pp. 12907-12915. ISSN 0021-9258.
9 November 2016
Britto, M. and Goulet, A. and Rizvi, S. and von Loeffelholz, O. and Moores, Carolyn A. and Cross, R.A. (2016) Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proceedings of the National Academy of Sciences of the United States of America 113 (47), E7483-E7489. ISSN 0027-8424.
2017
Atherton, Joe and Jiang, K. and Stangier, M.M. and Luo, Y. and Hua, S. and Houben, K. and von Hooff, J.J.E. and Joseph, Agnel Praveen and Scarabelli, G. and Grant, B.J. and Roberts, Anthony and Topf, Maya and Steinmetz, M. and Baldus, M. and Moores, Carolyn A. and Akhmanova, A. (2017) A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nature Structural and Molecular Biology 24 , pp. 931-943. ISSN 1545-9993.
11 August 2017
Atherton, Joseph and Yu, I-M. and Cook, Alexander and Muretta, J. and Joseph, Agnel Praveen and Major, J. and Sourigues, Y. and Clause, J. and Topf, Maya and Rosenfeld, S. and Houdusse, A. and Moores, Carolyn A. (2017) The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. eLife , ISSN 2050-084X.
7 November 2017
Locke, Julia and Joseph, Agnel Praveen and Pena, Alejandro and Mockel, M. and Mayer, T. and Topf, Maya and Moores, Carolyn A. (2017) Structural basis of human kinesin-8 function and inhibition. Proceedings of the National Academy of Sciences of the United States of America 114 (45), E9539-E9548. ISSN 0027-8424.
1 December 2017
Vemu, A. and Atherton, J. and Spector, J.O. and Moores, Carolyn A. and Roll-Mecak, A. and Blanchoin, L. (2017) Tubulin isoform composition tunes microtubule dynamics. Molecular Biology of the Cell 28 (25), pp. 3564-3572. ISSN 1059-1524.
13 December 2017
von Loeffelholz, Ottie and Venables, N.A. and Drummond, D.R. and Katsuki, M. and Cross, R. and Moores, Carolyn A. (2017) Nucleotide– and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics. Nature Communications 8 (1), ISSN 2041-1723.
2018
Atherton, J. and Stouffer, M. and Francis, F. and Moores, Carolyn A. (2018) Microtubule architecture in vitro and in cells revealed by cryo-electron tomography. Acta Crystallographica Section D: Structural Biology D74 , pp. 572-584. ISSN 2059-7983.
2 July 2018
Moores, Carolyn A. and Manka, S.W. (2018) The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability. Nature Structural & Molecular Biology 25 , pp. 607-615. ISSN 1545-9993.
12 October 2018
Manka, Szymon and Moores, Carolyn A. (2018) Microtubule structure by cryo-EM: snapshots of dynamic instability. Essays in Biochemistry 62 (6), pp. 737-751. ISSN 1744-1358.
16 January 2019
von Loeffelholz, O. and Peña, A. and Drummond, D.R. and Cross, R. and Moores, Carolyn A. (2019) Cryo-EM structure (4.5-Å) of Yeast Kinesin-5–Microtubule Complex reveals a distinct binding footprint and mechanism of drug resistance. Journal of Molecular Biology 431 (4), pp. 864-872. ISSN 0022-2836.
15 March 2019
Manka, Szymon and Moores, Carolyn A. (2019) Cryo-TEM and Biological Structure Determination. In: Ramesh, V. (ed.) Biomolecular and Bioanalytical Techniques: Theory, Methodology and Applications. John Wiley & Sons, Ltd, pp. 471-499. ISBN 9781119483960.
13 August 2019
Zeeshan, M. and Ferguson, D.J.P. and Abel, S. and Burrrell, A. and Rea, E. and Brady, D. and Daniel, E. and Delves, M. and Vaughan, S. and Holder, A.A. and Le Roch, K.G. and Moores, Carolyn A. and Tewari, R. (2019) Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission. Life Science Alliance 2 (4), e201900488. ISSN 2575-1077.
Adib, R. and Montgomery, J.M. and Atherton, J. and O’Regan, L. and Richards, M.W. and Straatman, K.R. and Roth, D. and Straube, A. and Bayliss, R. and Moores, Carolyn A. and Fry, A.M. (2019) Mitotic phosphorylation by NEK6 and NEK7 reduces microtubule affinity of EML4 to promote chromosome congression. Science Signaling 12 (594), eaaw2939. ISSN 1945-0877.
1 September 2019
von Loeffelholz, O. and Moores, Carolyn A. (2019) Cryo-EM structure of the Ustilago maydis kinesin-5 motor domain bound to microtubules. Journal of Structural Biology 207 (3), pp. 312-316. ISSN 1047-8477.
10 September 2019
Gubbels, M.-J. and Zeeshan, M. and Shilliday, F. and Liu, T. and Abel, S. and Mourier, T. and Ferguson, D.J.P. and Rea, E. and Stanway, R.R. and Roques, M. and Williams, D. and Daniel, E. and Brady, D. and Roberts, A.J. and Holder, A.A. and Pain, A. and Le Roch, K.G. and Moores, Carolyn A. and Tewari, R. (2019) Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission. PLoS Pathogens 15 (10), e1008048. ISSN 1553-7374.
20 November 2019
Atherton, Joe and Luo, Y. and Xiang, S. and Yang, C. and Rai, A. and Jiang, K. and Stangier, M. and Vemu, A. and Cook, A.D. and Wang, S. and Roll-Mecak, A. and Steinmetz, M.O. and Akhmanova, A. and Baldus, M. and Moores, Carolyn A. (2019) Structural determinants of microtubule minus end preference in CAMSAP CKK domains. Nature Communications 10 (1), ISSN 2041-1723.
1 January 2020
Cook, A.D. and Manka, Szymon W. and Wang, S. and Moores, Carolyn A. and Atherton, Joe (2020) A microtubule RELION-based pipeline for cryo-EM image processing. Journal of Structural Biology 209 (1), p. 107402. ISSN 1047-8477.
March 2020
Rai, A. and Liu, T. and Glauser, S. and Katrukha, E.A. and Estévez-Gallego, J. and Rodríguez-García, R. and Fang, W.-S. and Díaz, J.F. and Steinmetz, M.O. and Altman, K.-H. and Kapitein, L.C. and Moores, Carolyn A. and Akhmanova, A. (2020) Taxanes convert regions of perturbed microtubule growth into rescue sites. Nature Materials 19 , pp. 355-365. ISSN 1476-1122.
7 April 2020
Peña, A. and Sweeney, A. and Cook, A.D. and Topf, Maya and Moores, Carolyn A. (2020) Structure of microtubule-trapped Human Kinesin-5 and its mechanism of inhibition revealed using Cryoelectron Microscopy. Structure 28 (4), pp. 450-457. ISSN 0969-2126.
31 July 2020
von Loeffelholz, O. and Purkiss, A. and Cao, L. and Kjaer, S. and Kogata, N. and Romet-Lemonne, G. and Way, M. and Moores, Carolyn A. (2020) Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms. Biology Open , bio.054304. ISSN 2046-6390.
14 October 2020
Zeeshan, M. and Brady, D. and Stanway, R.R. and Moores, Carolyn A. and Holder, A.A. and Tewari, R. (2020) Plasmodium berghei Kinesin-5 associates with the Spindle Apparatus during cell division and is important for efficient production of infectious Sporozoites. Frontiers in Cellular and Infection Microbiology 10 , ISSN 2235-2988.
Manka, Szymon and Moores, Carolyn A. (2020) Pseudo-repeats in doublecortin make distinct mechanistic contributions to mi-crotubule regulation. EMBO Reports (e51534), ISSN 1469-3178.
30 November 2020
Atherton, Joe and Hummel, J.J.A. and Olieric, N. and Locke, J. and Peña, A. and Rosenfeld, S. and Steinmetz, M. and Hoogenraad, C.C. and Moores, Carolyn A. (2020) The mechanism of kinesin inhibition by kinesin binding protein. eLife , ISSN 2050-084X.
1 April 2021
Atherton, Joe and Moores, Carolyn A. (2021) Cryo-EM of kinesin-binding protein: challenges and opportunities from protein-surface interactions. Acta Crystallographica Section D Biological Crystallography D77 , pp. 411-423. ISSN 0907-4449.
18 October 2021
Gaillard, N. and Sharma, A. and Abbaali, I. and Liu, Tianyang and Shilliday, Fiona and Cook, Alex D. and Ehrhard, V. and Bangera, Mamata and Roberts, Anthony J. and Moores, Carolyn A. and Morrissette, N. and Steinmetz, M.O. (2021) Inhibiting parasite proliferation using a rationally designed anti-tubulin agent. EMBO Molecular Medicine (e13818), ISSN 1757-4684.
November 2021
Cook, Alex and Roberts, Anthony J. and Atherton, Joe and Tewari, R. and Topf, Maya and Moores, Carolyn A. (2021) Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. Journal of Biological Chemistry 297 (5), p. 101063. ISSN 0021-9258.
21 December 2021
Rai, A. and Liu, T. and Katrukha, E.A. and Estévez-Gallego, J. and Manka, Szymon and Paterson, I. and Díaz, F. and Kapitein, L.C. and Moores, Carolyn A. (2021) Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes. Proceedings of the National Academy of Sciences of the United States of America 118 (51), e2112261118. ISSN 0027-8424.
8 April 2022
Atherton, Joe and Stouffer, M. and Francis, F. and Moores, Carolyn A. (2022) Visualising the cytoskeletal machinery in neuronal growth cones using cryo-electron tomography. Journal of Cell Science 135 (7), ISSN 0021-9533.
28 July 2022
Zeeshan, M. and Rashpa, R. and Ferguson, D.J.P. and Abel, S. and Chahine, Z. and Brady, D. and Vaughan, S. and Moores, Carolyn A. and Le Roch, K.G. and Brochet, M. and Holder, A.A. and Tewari, R. (2022) Genome-wide functional analysis reveals key roles for kinesins in the mammalian and mosquito stages of the malaria parasite life cycle. PLoS Biology 20 (7), e3001704. ISSN 1545-7885.
16 November 2022
Liu, T. and Shilliday, F. and Cook, A.D. and Zeeshan, M. and Brady, D. and Tewari, R. and Sutherland, C.J. and Roberts, A.J. and Moores, Carolyn A. (2022) Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission. Nature Communications 13 (6988), ISSN 2041-1723.
24 January 2024
Liu, Tianyang and Cao, L. and Mladenov, M. and Jegou, A. and Way, M. and Moores, Carolyn A. (2024) Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament. Nature Structural and Molecular Biology , ISSN 1545-9993.
2 March 2024
Adler, A. and Bangera, Mamata and Beugelink, J.W. and Bahri, S. and van Ingen, H. and Moores, Carolyn A. and Baldus, M. (2024) A structural and dynamic visualization of the interaction between MAP7 and microtubules. Nature Communications 15 (1948), ISSN 2041-1723.